Herbicidal sulfonamides

ABSTRACT

The invention relates to certain sulfonamide compounds having substituents ortho to the sulfonylurea linkage, said substituents including alkenyl, substituted alkenyl, cycloalkenyl, substituted cycloalkenyl, alkynyl and substituted alkynyl.

RELATED APPLICATION

This is a continuation-in-part of application U.S. Ser. No. 768,158,filed Aug. 26, 1985 now abandoned which is a continuation-in-part ofU.S. Ser. No. 680,549, filed Dec. 11, 1984, now abandoned.

BACKGROUND OF THE INVENTION

The invention relates to certain sulfonamide compounds having alkenyl,cyclic alkenyl, alkynyl, substituted alkenyl, substituted cyclic alkenyland substituted alkynyl substituents ortho to the sulfonylurea linkage,agriculturally suitable compositions thereof and method of their use asherbicides or plant growth regulants.

In the most common situation, the control of undesired vegetation isdesired to permit the growth of useful crops such as cotton, rice, corn,wheat and soybeans, to name a few. Unchecked weed growth in such usefulcrops can cause significant losses, reducing profit to the farmer andincreasing costs to the consumer. In other situations, herbicides aredesired which will control all plant growth. Examples of areas in whichcomplete control of all vegetation is desired are areas around fuelstorage tanks, ammunition depots and industrial storage areas. There aremany products commercially available for these purposes, but the searchcontinues for products which are more effective, less costly andenvironmentally safe.

U.S. Pat. No. 4,368,069 discloses herbicidal benzenesulfonamides offormula ##STR1## wherein

R is --(CR₅ R₆)_(n) --R₂ ;

n is 0 or 1; and

R₂ may be C₅ -C₆ cycloalkenyl or C₂ -C₅ alkenyl.

South African patent application No. 83/3779 discloses herbicidalsulfonamides of formula ##STR2## wherein A is a radical of the formulaC.tbd.CR; and

R is, among others, a variety of alkyl or substituted alkyl groups.

Herbicidal thiophene sulfonamides are disclosed in European patentapplication (EP-A) No. 30,142, published June 10, 1981.

Herbicidal pyridinesulfonamides are disclosed in European patentapplication (EP-A) No. 13,480, published July 23, 1980.

U.S. Pat. No. 4,420,325 discloses herbicidal sulfonamides of thefollowing formula ##STR3## wherein

R₁ is F, Cl, Br, CF₃, C₁ -C₃ alkoxy, C₁ -C₃ alkyl, NO₂, CO₂ R₄, SO₂ R₅,SO₂ NR₆ R₇, SO₂ N(OCH₃)CH₃, SO₂ CH₂ CF₃, OSO₂ R₅ or CH₂ L; and

R₉ is H or C₁ -C₃ alkyl.

South African patent application No. 84/2722, published 10/13/84,discloses herbicidal sulfonamides of formula ##STR4## wherein

A is a radical of formula --CR₆ R₇ XR₈, CR₉ R₁₀ R₁₁ or CHR₇ SCQR₂₁ ;

R₆ is H, C₁ -C₄ alkyl or fluorine;

R₇ is H or CH₃ ;

X is O, S, SO or SO₂ ;

R₈ may be C₂ -C₅ haloalkenyl, C₃ -C₅ alkynyl, etc.

South African patent application No. 84/6610 discloses herbicidalpyrazolesulfonylureas of formula ##STR5## wherein

X is O or NR₆ ;

R₁ and R₂ are independently H, halogen, C₁ -C₆ alkyl, C₂ -C₆ alkenyl orC₂ -C₆ alkynyl, which are optionally substituted by 1-3 halogen atoms,C₁ -C₄ alkoxy, C₁ -C₄ alkylsulfenyl, C₁ -C₄ alkylsulfinyl, C₁ -C₄alkylsulfonyl, OH, etc.

South African patent application No. 83/6449, published 3/1/84,discloses herbicidal sulfonylureas of the formula ##STR6## wherein

R₃ is C₂ -C₁₀ alkenyl which is substituted by, inter alia, one or morefluorine or bromine atoms or by one or more hydroxyl, cyano or nitrogroups.

European Publication No. 132,230, published 1/23/85, discloses a processfor preparing sulfonylureas of the formula ##STR7## wherein

T denotes a substituted phenyl radical of formula ##STR8## X is, interalia, H, halogen, C₂ -C₄ alkynyl; R₁ is H or C₁ -C₄ alkyl; and ##STR9##

SUMMARY OF THE INVENTION

New compounds have been discovered which possess herbicidal activity aswell as agriculturally suitable compositions thereof and a method oftheir use as general and/or selective preemergent and/or postemergentherbicides or plant growth regulants. Accordingly the compounds of theinvention possessing herbicidal activity are compounds of the formula##STR10##

R is H or CH₃ ;

W₃ is O or S;

n is O or 1;

E is S(O)_(p) or Se;

p is 0, 1 or 2;

R₁ is H, C₁ -C₃ alkyl, C₁ -C₃ haloalkyl, halogen, nitro, CH₂ CN, CH₂OCH₃, CH₂ SCH₃, CN, C₁ -C₃ alkoxy, SO₂ NR^(I) R^(II), C₁ -C₃ alkylthio,C₁ -C₃ alkylsulfinyl, C₁ -C₃ alkylsulfonyl or CO₂ R^(III) ;

R^(I) is H, C₁ -C₄ alkyl, C₂ -C₃ cyanoalkyl, methoxy or ethoxy;

R^(II) is H, C₁ -C₄ alkyl or C₃ -C₄ alkenyl; or

R^(I) and R^(II) may be taken together as --(CH₂)₃ --, --(CH₂)₄ --,--(CH₂)₅ -- or --CH₂ CH₂ OCH₂ CH₂ --;

R^(III) is C₁ -C₄ alkyl, C₃ -C₄ alkenyl, C₃ -C₄ alkynyl, C₂ -C₄haloalkyl, C₂ -C₄ cyanoalkyl, C₅ -C₆ cycloalkyl, C₄ -C₇ cycloalkylalkylor C₂ -C₄ alkoxyalkyl;

R₂ is C₁ -C₃ alkyl;

W is W₁ or W₂ ;

W₁ is C₂ -C₈ alkenyl or C₄ -C₇ cycloalkenyl either of which may beoptionally substituted with 1-3 atoms of F, Cl or Br, OH, CN, NO₂, C₁-C₃ alkoxy, C₁ -C₃ alkylthio, C₁ -C₃ alkylsulfinyl, C₁ -C₃alkylsulfonyl, amino, C₂ -C₄ alkenyl, C₁ -C₃ alkylamino, di(C₁ -C₃alkyl)amino, (C₁ -C₃ alkylamino)sulfamoyl, di(C₁ -C₃alkylamino)sulfamoyl, OC(O)C₁ -C₃ alkyl, C(O)C₁ -C₃ alkoxy, OC(O)C₁ -C₃alkoxy, OSO₂ C₁ -C₃ alkyl, OSO₂ C₆ H₅, OSO₂ --4--CH₃ --C₆ H₄, phenyl orphenyl substituted with halogen, CH₃, OCH₃, SCH₃ or NO₂ ;

W₂ is C₂ alkynyl which may be substituted with phenyl or phenylsubstituted with halogen, CH₃, OCH₃, SCH₃ or NO₂ or W₂ is C₃ -C₈ alkynylwhich may be optionally substituted with 1-3 atoms of F, Cl or Br, OH,CN, NO₂, C₁ -C₃ alkoxy, C₁ -C₃ alkylthio, C₁ -C₃ alkylsulfinyl, C₁ -C₃alkylsulfonyl, amino, C₁ -C₃ alkylamino, di(C₁ -C₃ alkyl)amino, (C₁ -C₃alkylamino)sulfamoyl, di(C₁ -C₃ alkylamino)sulfamoyl, OC(O)C₁ -C₃ alkyl,OC(O)C₁ -C₃ alkoxy, OSO₂ C₁ -C₃ alkyl, OSO₂ C₆ H₅, OSO₂ --4--CH₃ --C₆H₄, phenyl or phenyl substituted with halogen, CH₃, OCH₃, SCH₃ or NO₂ ;

R₃ is H or C₁ -C₄ alkyl; ##STR11## X is H, C₁ -C₄ alkyl, C₁ -C₄ alkoxy,C₁ -C₄ haloalkoxy, C₁ -C₄ haloalkyl, C₁ -C₄ haloalkylthio, C₁ -C₄alkylthio, halogen, C₂ -C₅ alkoxyalkyl, C₂ -C₅ alkoxyalkoxy, amino, C₁-C₃ alkylamino or di(C₁ -C₃ alkyl)amino;

Y is H, C₁ -C₄ alkyl, C₁ -C₄ alkoxy, C₁ -C₄ haloalkoxy, C₁ -C₄haloalkylthio, C₁ -C₄ alkylthio, C₂ -C₅ alkoxyalkyl, C₂ -C₅alkoxyalkoxy, amino, C₁ -C₃ alkylamino, di(C₁ -C₃ alkyl)amino, C₃ -C₄alkenyloxy, C₃ -C₄ alkynyloxy, C₂ -C₅ alkylthioalkyl, C₁ -C₄ haloalkyl,C₃ -C₅ cycloalkyl,

C₂ -C₄ alkynyl, ##STR12## m is 2 or 3;

L₁ and L₂ are independently O or S;

R₄ and R₅ are independently C₁ -C₂ alkyl;

R₆ is H or CH₃ ;

Z is CH or N;

Y₁ is O or CH₂ ;

X₁ is CH₃, OCH₃, OC₂ H₅ or OCF₂ H;

Y₂ is H or CH₃ ;

X₂ is CH₃, OCH₃ or SCH₃ ;

Y₃ is CH₃, CH₂ CH₃ or CH₂ CF₃ ;

X₃ is CH₃ or OCH₃ ;

Y₄ is CH₃, OCH₃, OC₂ H₅ or Cl; and

X₄ is CH₃, OCH₃, OC₂ H₅ or CH₂ OCH₃ ; and their agriculturally suitablesalts; provided that

(a) when X is Cl, F, Br or I, then Z is CH and Y is OCH₃, OC₂ H₅,N(OCH₃)CH₃, NHCH₃, N(CH₃)₂ or OCF₂ H;

(b) when X or Y is OCF₂ H then Z is CH;

(c) when L is L-2 or L-3, then the W substituent and the sulfonylureabridge are on adjacent carbon atoms;

(d) when W₁ is C₃ alkenyl, then L is L-3, L-4, L-5 or L-6;

(e) when L is L-1, L then n is 1 and W is W₂ ;

(f) when L is L-1 and W₂ is C₂ or C₃ alkynyl, said group must besubstituted;

(g) when W₁ is C₃ -C₈ alkenyl or C₄ -C₇ cycloalkenyl substituted withOH, then the OH substituent is not bonded directly to the olefinicgroup;

(h) when L is L-3, then the sulfonylurea bridge is bonded at the 3- or5-position;

(i) when W₃ is S, then R is H, A is A-1, and Y is CH₃, OCH₃, OC₂ H₅, CH₂OCH₃, C₂ H₅, CF₃, SCH₃, OCH₂ CH═CH₂, OCH₂ C.tbd.CH, OCH₂ CH₂ OCH₃ orCH(OCH₃)₂ ;

(j) when the total number of carbon atoms of X and Y is greater thanfour, then the number of carbons of R₁ must be less than or equal to twoand the number of carbons of W must be less than or equal to four; and

(k) when L is L-2, L-3, L-4 or L-5, then W₁ is other than C₂ -C₈ alkenylsubstituted with 1-3 atoms of F, Cl or Br.

In the above definitions, the term "alkyl" used either alone or incompound words such as "alkylthio" or "haloalkyl", denotes straightchain or branched alkyl, e.g., methyl, ethyl, n-propyl, isopropyl or thedifferent butyl isomers.

Alkoxy denotes methoxy, ethoxy, n-propoxy, isopropoxy and the differentbutoxy isomers.

Alkenyl denotes straight chain or branched alkenes, e.g., vinyl,1-propenyl, 2-propenyl, 3-propenyl and the different butenyl, pentenyl,hexenyl, heptenyl and octenyl isomers.

Alkynyl denotes straight chain or branched alkynes, e.g., ethynyl,1-propynyl, 2-propynyl and the different butynyl, pentynyl, hexynyl,heptynyl and octynyl isomers.

Cyclohexenyl means cyclobutenyl, cyclopentenyl, cyclohexenyl andcycloheptenyl.

The term "halogen", either alone or in compound words such as"haloalkyl", denotes fluorine, chlorine, bromine or iodine.

In terms such as C₂ -C₃ alkylthioalkyl, the specified number of carbonatoms is meant to define the total number of carbon atoms in thatsubstituent group. For example, C₂ -C₃ alkylthioalkyl would designateCH₂ SCH₃, CH₂ SC₂ H₅, CH₂ CH₂ SCH₃ or CH(CH₃)SCH₃, and C₂ -C₅alkoxyalkoxy would represent OCH₂ OCH₃ through O(CH₂)₄ OCH₃ or OCH₂O(CH₂)₃ CH₃ and the various structural isomers embraced therein.

Alkylsulfonyl denotes methylsulfonyl, ethylsulfonyl and the differentpropylsulfonyl isomers.

Alkylthio, alkylsulfinyl, alkylamino, alkylsulfamoyl, etc. are definedin an analogous manner.

The compounds of the invention which are preferred for reasons ofincreased ease of synthesis and/or greater herbicidal efficacy are:

(1) Compounds of Formula I where

R is H; and

W₃ is O.

(2) Compounds of Preferred 1 where

R₁ is H, F, Cl, NO₂, C₁ -C₂ alkyl, C₁ -C₂ haloalkyl, C₁ -C₂ alkoxy, C₁-C₂ alkylthio, CH₂ OCH₃ or CH₂ SCH₃, and is not para to the sulfonylureabridge.

(3) Compounds of Preferred 2 where

X is CH₃, OCH₃, OC₂ H₅, Cl, F, Br, OCF₂ H, CH₂ F, OCH₂ CH₂ F, OCH₂ CHF₂,OCH₂ CF₃, CF₃, CH₂ Cl or CH₂ Br; and

Y is H, C₁ -C₃ alkyl, OCH₃, OC₂ H₅, CH₂ OCH₃, NHCH₃, N(OCH₃)CH₃,N(CH₃)₂, CF₃, SCH₃, OCH₂ CH═CH₂, OCH₂ C.tbd.CH, CH₂ OC₂ H₅, OCH₂ CH₂OCH₃, CH₂ SCH₃, OCF₂ H, SCF₂ H, cyclopropyl, C.tbd.CH or C.tbd.CCH₃.

(4) Compounds of Preferred 3 where

W₁ is C₂ -C₅ alkenyl which may be optionally substituted by 1-3 atoms ofF, Cl or Br, OH, OCH₃, OC(O)CH₃, OSO₂ CH₃, CN or SCH₃, or W₁ is C₅ -C₆cycloalkenyl; and

W₂ is C.tbd.CC₆ H₅ or C₃ -C₅ alkynyl which may be optionally substitutedby 1-3 atoms of F, Cl or Br, OH, OCH₃, OC(O)CH₃, CN or SCH₃.

(5) Compounds of Preferred 4 where

A is A-1;

X is CH₃, OCH₃, OC₂ H₅, Cl or OCF₂ H;

Y is CH₃, C₂ H₅, OCH₃, CH₂ OCH₃, CH(OCH₃)₂, OCF₂ H, NHCH₃, N(CH₃)₂ orcyclopropyl; and

R₁ is H, CH₃, OCH₃ or Cl.

(6) Compounds of Preferred 5 where

L is L-1.

(7) Compounds of Preferred 5 where

L is L-2; and

W is W₁.

(8) Compounds of Preferred 5 where

L is L-2; and

W is W₂.

(9) Compounds of Preferred 5 where

L is L-3; and

W is W₁.

(10) Compounds of Preferred 5 where

L is L-3; and

W is W₂.

(11) Compounds of Preferred 5 where

L is L-4; and

W is W₁.

(12) Compounds of Preferred 5 where

L is L-4; and

W is W₂.

(13) Compounds of Preferred 5 where

L is L-5; and

W is W₁.

(14) Compounds of Preferred 5 where

L is L-5; and

W is W₂.

(15) Compounds of Preferred 5 where

L is L-6; and

W is W₁.

(16) Compounds of Preferred 5 where

L is L-6; and

W is W₂.

(17) Compounds of Preferred 5 where

L is L-7.

Compound specifically preferred for reasons of their expected greatestease of synthesis and/or greatest herbicidal efficacy are:

2-(1-cyclohexen-2-yl)-N-[4-methoxy-6-methylpyrimidin-2-yl)aminocarbonyl]-3-thiophenesulfonamide,m.p. 190°-192° C.;

2-(1-cyclohexen-2-yl)-N-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)aminocarbonyl]-3-thiophenesulfonamide,m.p. 169°-171° C.; and

N-[(4-methoxy-6-methylpyrimidin-2-yl)aminocarbonyl]-1-methyl-4-(1-propenyl)-1H-pyrazole-5-sulfonamide,m.p. 155°-158° C.

DETAILED DESCRIPTION OF THE INVENTION Synthesis

The compounds of Formula I can be prepared by reacting an appropriatesulfonyl isocyanate or sulfonyl isothiocyanate, II, with anappropriately substituted aminoheterocycle, III, as shown in Equation 1,where R, W₃, A and L are as previously defined. ##STR13##

The reaction is best performed in an inert solvent such as methylenechloride or toluene at 25° to 100° C., for 1 to 24 hours. Isolation ofthe product can be achieved by concentrating the solution andtrituration with an appropriate solvent such as butyl chloride.

Alternatively, compounds of Formula I, where W₃ is O, can be prepared byreacting the sulfonamides of Formula IV with the carbamates of Formula V(R'=CH₃) in the presence of an excess of trimethylaluminum, as shown inEquation 2, where L, R and A are as previously defined, provided R₁ isother than CO₂ R^(III). ##STR14##

The reactions are best performed in an inert solvent such as methylenechloride at the reflux point of the solution (40° C.) for 10 to 24hours. Isolation of the product is best achieved by exposing thereaction mixture to acetic acid, separation of the layers andconcentrating the organic layer to a solid.

Alternatively, compounds of Formula I can be prepared by exposing aphenyl carbamate V (R'═Ph) to the sulfonamide IV in an appropriatesolvent such as dioxane at 25° to 100° C. in the presence of a strongbase such as 1,8-diazabicyclo[5.4.0]undec-7-ene; acid workup affords thedesired product, as disclosed in European patent application (EP-A) No.44,807. Compounds of Formula I can also be prepared from a phenylcarbamate V and the tert-butyldimethylsilane-protected sulfonamide IV(LSO₂ NHSi(CH₃)₂ -t-Bu). Addition of tetrabutylammonium fluoride to amixture of the carbamate and sulfonamide affords, after workup, thedesired product. The required carbamates can be prepared from thecorresponding amines, III, and dimethyl- or diphenylcarbonate or methyl-or phenylchloroformate and a base such as sodium hydride.

The sulfonyl isocyanates, II, used in the preparation of I are known inthe art and can be prepared by known methods. For example, isocyanatescan be prepared by exposing an appropriate benzene or heterocyclicsulfonamide to phosgene in the presence of an alkyl isocyanate and anamine catalyst such as 1,4-diazabicyclo[2.2.2]octane at the reflux pointof the solvent. See H. Ulrich and A. A. Y. Sayigh, Newer Methods ofPreparative Organic Chemistry, Vol. VI, p. 223-241, Academic Press, NewYork and London, W. Forest Ed.

Sulfonyl isothiocyanates of Formula II, where W₃ is S, can be preparedaccording to the method of K. Hartke, Arch. Pharm., 299, 174 (1966).

The intermediate sulfonamides IV used to prepare the correspondingsulfonylureas I can be prepared in a variety of ways. For example, 1 maybe prepared from 2 via the lithiation, condensation protocol outlined inEquation 3. ##STR15##

This same methodology can also be applied to other sulfonamides such asthiophene 3 and pyrazole 4 as outlined in Equation 4. The examplesdepicted are meant to be exemplary and the methodology is applicable toa wide range of values for W and the various aromatic thiophene,pyrazole, pyridine and benzyl isomers. ##STR16##

Sulfonamides such as 1, 3 and 4 can also be prepared from thecorresponding olefin or alkyne as outlined in Equation 5, where W is aspreviously defined. ##STR17##

Olefinic sulfonamides such as 5 can be prepared from themethyl-substituted t-butylsulfonamide 6, as outlined in Equation 6. Hereagain, the example is intended to be exemplary and would be applicableto a wide variety of values for R₁ and W₁. ##STR18##

The sulfonamides IV of the invention such as 8 or 9 can also be preparedvia a modification of the Ullman reaction as outlined in Equation 7.##STR19##

Intermediates such as 9 can also be used to prepare the correspondingolefins such as 8 via catalytic hydrogenation, employing a catalyst suchas Lindlar catalyst.

Condensation of protected sulfonamides, for example 3c, with ketones andaldehydes followed by elimination also affords the desired sulfonamides.This is outlined in Equation 8. ##STR20##

Sulfonamides such as 3d can be prepared via the aldehyde 3e by aKnoevenagel type condensation with active methylene compounds as shownin Equation 9. Appropriate active methylene compounds include malonicesters, malononitrile, α-cyanoacetates, α-nitroacetates to name a few.##STR21##

Similar condensation with pyrazole, pyridine or benzene aldehydesprovides access to the corresponding difunctionalized alkenylsulfonamides.

One skilled in the art will recognize that many of the methods describedabove can result in the formation of two possible geometrical isomersabout the carbon-carbon double bond. This invention is meant toencompass all isomers. In cases where a mixture is obtained, the isomerscan be separated by standard methods, such as fractionalrecrystallization or chromatography. Alternatively, the compounds can beused as a mixture of double bond isomers.

The intermediate pyrazole, thiophene, pyridine and benzyl sulfonamidesare well known to one skilled in the art. For further informationpertaining to their preparation see EP-A-95,925; EP-A-30,142;EP-A-13,480; EP-A-51,466; and U.S. Pat. No. 4,420,325. The lithiation ofboth aromatic and heterocyclic compounds is well known to one skilled inthe art. For further information pertaining to this methodology seeStowell, J. C. "Carbanions in Organic Synthesis", John Wiley & Sons: NewYork, 1979; Snieckus, V. Tetrahedron Lett. 26, 1145 (1985) and ibid,1149 (1985).

The heterocyclic amines of Formula III can be prepared by methods knownin the literature or simple modifications thereof, by those skilled inthe art. For instance, EP-A-84,224 (published July 27, 1983) and W.Braker et al, J. Am. Chem. Soc. 1947, 69, 3072 describe methods forpreparing aminopyrimidines and triazines substituted by acetal groups.Also, South African Patent Application Nos. 825,045 and 825,671 describemethods for preparing aminopyrimidines and triazines substituted byhaloalkyl or haloalkylthio groups such as OCH₂ CH₂ F, OCH₂ CF₃, SCF₂ H,and OCF₂ H among other groups. South African Patent Application No.837,434 (published Oct. 5, 1983) describes methods for the synthesis ofcyclopropylpyrimidines and triazines substituted by such groups asalkyl, haloalkyl, alkoxy, haloalkoxy, alkylamino, dialkylamino, andalkoxyalkyl.

The 5,6-dihydrofuro[2.3-d]pyrimidin-2-amines, and thecyclopenta[d]pyrimidin-2-amines, of Formula III, where A is A-2, and the6,7-dihydro-5H-pyrano-[2.3-d]pyrimidin-2-amines, of Formula III, where Ais A-3, can be prepared as described in EP-A No. 15,863. Thefuro[2.3-d]pyrimidin-2-amines, of Formula III, where A is A-4, aredescribed in EP-A No. 46,677. Heterocycles of formula III, where A isA-5, can be prepared as described in EP-A No. 73,562. Heterocycles ofFormula III, where A is A-6, can be prepared by methods taught inEP-A-94,260. Compounds of Formula III, where A is A-7, can be preparedby methods taught in EP-A-125,864.

In addition, general methods for preparing aminopyrimidines andtriazines have been reviewed in the following publications.

"The Chemistry of Heterocyclic Compounds", a series published byInterscience Publishers, Inc., New York an London;

"Pyrimidines", Vol. 16 of the same series by D. J. Brown;

"s-Triazines and Derivatives", Vol. 13 of the same series by E. M.Smolin and L. Rapaport; and

F. C. Schaefer, U.S. Pat. No. 3,154,547 and K. R. Huffman and F. C.Schaefer, J. Org. Chem., 28, 1812 (1963), which describe the synthesisof triazines.

Agriculturally suitable salts of compounds of Formula I are also usefulherbicides and can be prepared in a number of ways known to the art. Forexample, metal salts can be made by contacting compounds of Formula Iwith a solution of an alkali or alkaline earth metal salt having asufficiently basic anion (e.g., hydroxide, alkoxide or carbonate).Quaternary amine salts can be made by similar techniques.

Salts of compounds of Formula I can also be prepared by exchange of onecation for another. Cationic exchange can be effected by directcontacting of an aqueous solution of a salt of a compound of Formula I(e.g., alkali metal or quaternary amine salt) with a solution containingthe cation to be exchanged. This method is most effective when thedesired salt containing the exchanged cation is insoluble in water,e.g., a copper salt, and can be separated by filtration.

Exchange may also be effected by passing an aqueous solution of a saltof a compound of Formula I (e.g., an alkali metal or quaternary aminesalt) through a column packed with a cation exchange resin containingthe cation to be exchanged. In this method, the cation of the resin isexchanged for that of the original salt and the desired product iseluted from the column. This method is particularly useful when thedesired salt is water-soluble, e.g., a potassium, sodium or calciumsalt.

Acid addition salts, useful in this invention, can be obtained byreacting a compound of Formula I with a suitable acid, e.g.,p-toluenesulfonic acid, trichloroacetic acid or the like.

The preparation of the compounds of this invention is illustrated by thefollowing examples.

EXAMPLE 1 Preparation of 2-(1-Cyclohexenyl)-3-thiophenesulfonamide

A solution of 3-bromo-2-(1-cyclohexenyl)-thiophene (prepared by themethod of N. Gjos and S. Gronowitz, Acta. Chem. Scan., 26, 1851-59,(1972)) (8.0 g, 32.9 mmol) in ether (30 ml) was added dropwise to astirring solution of n-butyllithium (1.37M, 25.2 ml, 34.6 mmol) in ether(60 ml) precooled to -78° C. The solution was stirred another 30 minutesat -78° C. and was then treated with sulfuryl chloride (3.2 ml, 40 mmol)in hexane (10 ml). After an additional 30 minutes at -78° C., anhydrousammonia (9 ml, 300 mmol) was added, the suspension warmed to 25° C. andpoured into ether, washed with water and brine, dried over magnesiumsulfate and reduced in volume. The product was crystallized bytrituration with butyl chloride and hexane affording 2.51 g white solid(31%) m.p. 115°-121° C.

EXAMPLE 2 Preparation of2-(1-Cyclohexen-2-yl)-N-[(4-methoxy-6-methylpyrimidin-2-yl)aminocarbonyl]-3-thiophenesulfonamide

To a stirring solution of 2-(1-cyclohexenyl)-3-thiophenesulfonamide (160mg, 0.657 mmol), and 4-methyl-6-methoxy-2-aminophenoxycarbonylpyrimidine (180 mg, 0.69 mmol) in 15 ml of acetonitrile was added1,8-diazabicyclo[5.4.0]undec-7-ene (105 mg, 0.69 mmol). The reaction wasstirred overnight, poured into water, acidified with acetic acid andextracted with methylene chloride, dried over magnesium sulfate andconcentrated to yield the desired product, 170 mg, m.p. 190°-192° C.

NMR(δ) (d₆ -DMSO) (200 MHz): 1.3-2.4 (m, with s at 2.10, 11H); 3.79 (s,3H); 5.8-6.0 (m, 1H); 6.42 (s, 1H), 7.30 and 7.44 (AB q, J=5.4 Hz, 2H).

EXAMPLE 3 Preparation of4-(1-Hydroxypropyl)-1-methyl-5-tert-butylpyrazolesulfonamide

To a cooled solution of n-butyl lithium (1.8 g, 27.9 mmol) in 150 ml oftetrahydrofuran was added4-bromo-5-tert-butylsulfonamide-N-methylpyrazole. After stirring for 30minutes at 0°-78° C., propionaldehyde (1.5 g, 27.9 mmole) was addeddropwise. After standard workup, a red oil was isolated. Crystallizationfrom ethyl acetate/hexane afforded 3.1 g of the desired compound, m.p.113°-115° C.

EXAMPLE 4 Preparation of 4-(2-Propenyl)-1-methyl-5-pyrazole sulfonamide

The alcohol (3.0 g) from Example 3 was stirred in 25 ml oftrifluoroacetic acid at 68° C. for 30 minutes. The solution was allowedto cool to room temperature, and the volatile components were removed invacuo to afford 510 mg of the desired sulfonamide, m.p. 157°-161° C.

EXAMPLE 5 Preparation ofN-[(4,6-Dimethoxypyrimidin-2-yl)aminocarbonyl]-1-methyl-4-(1-propenyl)-1H-pyrazole-5-sulfonamide

The sulfonamide from Example 4 (150 mg, 0.7 mmol) and thephenylcarbamate of 4,6-dimethoxy-2-aminopyrimidine (202 mg, 0.7 mmol)were dissolved in 5 ml of acetonitrile.1,8-Diazabicyclo[5.4.0]undec-7-ene (112 mg, 0.7 mmol) was added and thereaction was stirred for 30 minutes. Addition of 5 ml of 5% hydrochloricacid resulted in a solid, which was collected and dried to afford 280 mgof the desired product, m.p. 154°-156° C.

NMR (200 MHz, CDCl₃ ): δ 1.84 (d, 3H); 3.56 (s, 6H); 4.21 (s, 3H); 5.80(s, 1H); 6.2 (d, q, 1H); 6.57 (d, d, 1H); 7.43 (br s, 1H); 7.61 (s, 1H).The NMR was indicative of a cis:trans mixture of 1:7.

Applying the methods described in Equations 1-8 and Examples 1-5, oneskilled in the art can prepare the compounds of Tables I-Va.

    ______________________________________                                        TABLE OF STRUCTURES                                                           ______________________________________                                        General Structure I                                                            ##STR22##                                                                    General Structure II                                                           ##STR23##                                                                    General Structure III                                                          ##STR24##                                                                    L-2 is                                                                         ##STR25##                                                                    L-3 is                                                                         ##STR26##                                                                    General Structure IIIa                                                         ##STR27##                                                                    L-2 is                                                                         ##STR28##                                                                    General Structure IIIb                                                         ##STR29##                                                                    L-2 is                                                                         ##STR30##                                                                    L-3 is                                                                         ##STR31##                                                                    General Structure IV                                                           ##STR32##                                                                    General Structure V                                                            ##STR33##                                                                    L-2 and L-3 are as in General Structure III.                                  General Structure Va                                                           ##STR34##                                                                    L-2 and L-3 are as in General Structure IIIa.                                 ______________________________________                                    

                  TABLE I                                                         ______________________________________                                        General Structure I                                                           R    R.sub.1                                                                              R.sub.3                                                                              E     X     Y     Z    m.p. (°C.)                   ______________________________________                                        H    H      H      S     CH.sub.3                                                                            CH.sub.3                                                                            CH   142-145                             H    H      H      S     CH.sub.3                                                                            OCH.sub.3                                                                           CH   141-143                             H    H      H      S     OCH.sub.3                                                                           OCH.sub.3                                                                           CH   131-134                             H    H      H      S     CH.sub.3                                                                            CH.sub.3                                                                            N    165-169                             H    H      H      S     CH.sub.3                                                                            OCH.sub.3                                                                           N    152-156                             H    H      H      S     OCH.sub.3                                                                           OCH.sub.3                                                                           N    140-142                             H    H      H      S     Cl    OCH.sub.3                                                                           CH   186-191                             H    H      H      SO    CH.sub.3                                                                            CH.sub.3                                                                            CH                                       H    H      H      SO    CH.sub.3                                                                            OCH.sub.3                                                                           CH                                       H    H      H      SO    OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                       H    H      H      SO    CH.sub.3                                                                            CH.sub.3                                                                            N                                        H    H      H      SO    CH.sub.3                                                                            OCH.sub.3                                                                           N                                        H    H      H      SO    OCH.sub.3                                                                           OCH.sub.3                                                                           N                                        H    H      H      SO    Cl    OCH.sub.3                                                                           CH                                       H    H      H      SO.sub.2                                                                            CH.sub.3                                                                            CH.sub.3                                                                            CH   210-212                             H    H      H      SO.sub.2                                                                            CH.sub.3                                                                            OCH.sub.3                                                                           CH                                       H    H      H      SO.sub.2                                                                            OCH.sub.3                                                                           OCH.sub.3                                                                           CH   226-229                             H    H      H      SO.sub.2                                                                            CH.sub.3                                                                            CH.sub.3                                                                            N    185-188                             H    H      H      SO.sub.2                                                                            CH.sub.3                                                                            OCH.sub.3                                                                           N                                        H    H      H      SO.sub.2                                                                            OCH.sub.3                                                                           OCH.sub.3                                                                           N    165-179                             H    H      H      SO.sub.2                                                                            Cl    OCH.sub.3                                                                           CH   207-209                             H    H      H      Se    CH.sub.3                                                                            CH.sub.3                                                                            CH   187-190                             H    H      H      Se    CH.sub.3                                                                            OCH.sub.3                                                                           CH   165-167                             H    H      H      Se    OCH.sub.3                                                                           OCH.sub.3                                                                           CH   184-186                             H    H      H      Se    CH.sub.3                                                                            CH.sub.3                                                                            N    177-181                             H    H      H      Se    CH.sub.3                                                                            OCH.sub.3                                                                           N    163-166                             H    H      H      Se    OCH.sub.3                                                                           OCH.sub.3                                                                           N    147-151                             H    H      H      Se    Cl    OCH.sub.3                                                                           CH                                       CH.sub.3                                                                           H      H      Se    OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                       CH.sub.3                                                                           H      CH.sub.3                                                                             Se    CH.sub.3                                                                            OCH.sub.3                                                                           CH                                       H    CH.sub.3                                                                             H      Se    OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                       H    H      CH.sub.3                                                                             S     CH.sub.3                                                                            CH.sub.3                                                                            CH   143-147                             H    H      CH.sub.3                                                                             S     CH.sub.3                                                                            OCH.sub.3                                                                           CH   136-139                             H    H      CH.sub.3                                                                             S     OCH.sub.3                                                                           OCH.sub.3                                                                           CH   148-150                             H    H      CH.sub.3                                                                             S     CH.sub.3                                                                            CH.sub.3                                                                            N    151-153                             H    H      CH.sub.3                                                                             S     CH.sub.3                                                                            OCH.sub.3                                                                           N    164-169                             H    H      CH.sub.3                                                                             S     OCH.sub.3                                                                           OCH.sub.3                                                                           N    154-160                             H    H      CH.sub.3                                                                             S     Cl    OCH.sub.3                                                                           CH   141-143                             H    H      CH.sub.3                                                                             Se    CH.sub.3                                                                            CH.sub.3                                                                            CH   155-158                             H    H      CH.sub.3                                                                             Se    OCH.sub.3                                                                           CH.sub.3                                                                            CH   159-161                             H    H      CH.sub.3                                                                             Se    OCH.sub.3                                                                           OCH.sub.3                                                                           CH     145-148.5                         H    H      CH.sub.3                                                                             Se    CH.sub.3                                                                            CH.sub.3                                                                            N    173-176                             H    H      CH.sub.3                                                                             Se    OCH.sub.3                                                                           CH.sub.3                                                                            N      185-186.5                         H    H      CH.sub.3                                                                             Se    OCH.sub.3                                                                           OCH.sub.3                                                                           N    182.5-184                           H    H      CH.sub.3                                                                             Se    Cl    OCH.sub.3                                                                           CH                                       H    H      CH.sub.3                                                                             SO    CH.sub.3                                                                            CH.sub.3                                                                            CH                                       H    H      CH.sub.3                                                                             SO    CH.sub.3                                                                            OCH.sub.3                                                                           CH                                       H    H      CH.sub.3                                                                             SO    OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                       H    H      CH.sub.3                                                                             SO    CH.sub.3                                                                            CH.sub.3                                                                            N                                        H    H      CH.sub.3                                                                             SO    CH.sub.3                                                                            OCH.sub.3                                                                           N                                        H    H      CH.sub.3                                                                             SO    OCH.sub.3                                                                           OCH.sub.3                                                                           N                                        H    H      CH.sub.3                                                                             SO    Cl    OCH.sub.3                                                                           CH                                       H    H      CH.sub.3                                                                             SO.sub.2                                                                            CH.sub.3                                                                            CH.sub.3                                                                            CH                                       H    H      CH.sub.3                                                                             SO.sub.2                                                                            CH.sub.3                                                                            OCH.sub.3                                                                           CH                                       H    H      CH.sub.3                                                                             SO.sub.2                                                                            OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                       H    H      CH.sub.3                                                                             SO.sub.2                                                                            CH.sub.3                                                                            CH.sub.3                                                                            N                                        H    H      CH.sub.3                                                                             SO.sub.2                                                                            CH.sub.3                                                                            OCH.sub.3                                                                           N                                        H    H      CH.sub.3                                                                             SO.sub.2                                                                            OCH.sub.3                                                                           OCH.sub.3                                                                           N                                        H    H      CH.sub.3                                                                             SO.sub.2                                                                            Cl    OCH.sub.3                                                                           CH                                       ______________________________________                                    

                  TABLE II                                                        ______________________________________                                        General Structure II                                                                                                     m.p.                               W          R      R.sub.1 X     Y     Z    (°C.)                       ______________________________________                                        C.tbd.CHCH.sub.2 CH.sub.3                                                                H      H       CH.sub.3                                                                            CH.sub.3                                                                            CH                                      C.tbd.CHCH.sub.2 CH.sub.3                                                                H      H       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                      C.tbd.CHCH.sub.2 CH.sub.3                                                                H      H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                      C.tbd.CHCH.sub.2 CH.sub.3                                                                H      H       CH.sub.3                                                                            CH.sub.3                                                                            N                                       C.tbd.CHCH.sub.2 CH.sub.3                                                                H      H       CH.sub.3                                                                            OCH.sub.3                                                                           N                                       C.tbd.CHCH.sub.2 CH.sub.3                                                                H      H       OCH.sub.3                                                                           OCH.sub.3                                                                           N                                       C.tbd.CHCH.sub.2 CH.sub.3                                                                H      H       Cl    OCH.sub.3                                                                           CH                                      C.tbd.C--CH.sub.2 Ph                                                                     H      H       CH.sub.3                                                                            CH.sub.3                                                                            CH                                      C.tbd.C--CH.sub.2 Ph                                                                     H      H       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                      C.tbd.C--CH.sub.2 Ph                                                                     H      H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                      C.tbd.C--CH.sub.2 Ph                                                                     H      H       CH.sub.3                                                                            CH.sub.3                                                                            N                                       C.tbd.C--CH.sub.2 Ph                                                                     H      H       CH.sub.3                                                                            OCH.sub.3                                                                           N                                       C.tbd.C--CH.sub.2 Ph                                                                     H      H       OCH.sub.3                                                                           OCH.sub.3                                                                           N                                       C.tbd.C--CH.sub.2 Ph                                                                     H      H       Cl    CH.sub.3                                                                            CH                                      C.tbd.C--CH.sub.2 Br                                                                     H      H       CH.sub.3                                                                            CH.sub.3                                                                            CH                                      C.tbd.C--CH.sub.2 Br                                                                     H      H       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                      C.tbd.C--CH.sub.2 Br                                                                     H      H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                      C.tbd.C--CH.sub.2 Br                                                                     H      H       CH.sub.3                                                                            CH.sub.3                                                                            N                                       C.tbd.C--CH.sub.2 Br                                                                     H      H       CH.sub.3                                                                            OCH.sub.3                                                                           N                                       C.tbd.C--CH.sub.2 Br                                                                     H      H       OCH.sub.3                                                                           OCH.sub.3                                                                           N                                       C.tbd.C--CH.sub.2 Br                                                                     H      H       Cl    OCH.sub.3                                                                           CH                                      C.tbd.C--Ph                                                                              H      H       CH.sub.3                                                                            CH.sub.3                                                                            CH                                      C.tbd.C--Ph                                                                              H      H       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                      C.tbd.C--Ph                                                                              H      H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                      C.tbd.C--Ph                                                                              H      H       CH.sub.3                                                                            CH.sub.3                                                                            N                                       C.tbd.C--Ph                                                                              H      H       CH.sub.3                                                                            OCH.sub.3                                                                           N                                       C.tbd.C--Ph                                                                              H      H       OCH.sub.3                                                                           OCH.sub.3                                                                           N                                       C.tbd.C--Ph                                                                              H      H       Cl    OCH.sub.3                                                                           CH                                      C.tbd.CCH.sub.2 OCH.sub.3                                                                CH.sub.3                                                                             H       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                      C.tbd.CCH.sub.2 OCH.sub.3                                                                CH.sub.3                                                                             H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                      C.tbd.CCH.sub.2 OCH.sub.3                                                                CH.sub.3                                                                             H       CH.sub.3                                                                            CH.sub.3                                                                            N                                       C.tbd.CCH.sub.2 OCH.sub.3                                                                CH.sub.3                                                                             H       CH.sub.3                                                                            OCH.sub.3                                                                           N                                       C.tbd.CCH.sub.2 OCH.sub.3                                                                CH.sub.3                                                                             H       OCH.sub.3                                                                           OCH.sub.3                                                                           N                                       C.tbd.CCH.sub.2 OCH.sub.3                                                                CH.sub.3                                                                             H       Cl    OCH.sub.3                                                                           CH                                      C.tbd.CCH.sub.2 OCH.sub.3                                                                H      CH.sub.3                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                      C.tbd.CCH.sub.2 Cl                                                                       H      CH.sub.3                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                           N                                       C.tbd.CCH.sub.2 Cl                                                                       H      CH.sub.3                                                                              OCH.sub.3                                                                           CH.sub.3                                                                            CH                                      C.tbd.C--CH.sub.2 CH.sub.3                                                               H      SCH.sub.3                                                                             OCH.sub.3                                                                           CH.sub.3                                                                            CH                                      C.tbd.C--CH.sub.2 CH.sub.3                                                               H      SCH.sub.3                                                                             OCH.sub.3                                                                           OCH.sub.3                                                                           N                                       C.tbd.C--CH.sub.2 CH.sub.3                                                               H      Cl      OCH.sub.3                                                                           OCH.sub.3                                                                           N                                       C.tbd.C--CH.sub.2 CH.sub.3                                                               H      OCH.sub.3                                                                             OCH.sub.3                                                                           CH.sub.3                                                                            N                                       C.tbd.C--CH.sub.2 CH.sub.3                                                               H      OCH.sub.3                                                                             OCH.sub.3                                                                           OCH.sub.3                                                                           N                                       C.tbd.C--CH.sub.2 CH.sub.3                                                               H      OCH.sub.3                                                                             CH.sub.3                                                                            OCH.sub.3                                                                           CH                                      C.tbd.C--CH.sub.2 CH.sub.3                                                               H      OCH.sub.3                                                                             Cl    OCH.sub.3                                                                           CH                                      ______________________________________                                    

                                      TABLE III                                   __________________________________________________________________________    General Structure III                                                                                                       m.p.                            L  n W                 R  R.sub.1                                                                          R.sub.2                                                                          X    Y     Z  (°C.)                    __________________________________________________________________________    L-2                                                                              0 CHCH.sub.2        H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              0 CHCH.sub.2        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHCH.sub.2        H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHCH.sub.2        H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              0 CHCH.sub.2        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0 CHCH.sub.2        H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 CHCH.sub.2        H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHCHCN            H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              0 CHCHCN            H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHCHCN            H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHCHCN            H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              0 CHCHCN            H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0 CHCHCN            H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 CHCHCN            H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHCHOCH.sub.3     H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              0 CHCHOCH.sub.3     H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHCHOCH.sub.3     H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHCHOCH.sub.3     H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              0 CHCHOCH.sub.3     H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0 CHCHOCH.sub.3     H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 CHCHOCH.sub.3     H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHCHPh            H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              0 CHCHPh            H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHCHPh            H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHCHPh            H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              0 CHCHPh            H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0 CHCHPh            H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 CHCHPh            H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              0 C(CH.sub.3)CHPh   H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              0 C(CH.sub.3)CHPh   H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0 C(CH.sub.3)CHPh   H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 C(CH.sub.3)CHPh   H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              0 C(CH.sub.3)CHPh   H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0 C(CH.sub.3)CHPh   H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 C(CH.sub.3)CHPh   H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              0                                                                                ##STR35##        H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH 186-190                         L-2                                                                              0                                                                                ##STR36##        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH 182-185                         L-2                                                                              0                                                                                ##STR37##        H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH 178-180                         L-2                                                                              0                                                                                ##STR38##        H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              0                                                                                ##STR39##        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N  152-156                         L-2                                                                              0                                                                                ##STR40##        H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N  145-148                         L-2                                                                              0                                                                                ##STR41##        H  H  -- Cl   OCH.sub.3                                                                           CH 192-195                         L-2                                                                              0                                                                                ##STR42##        H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH 208-211                         L-2                                                                              0                                                                                ##STR43##        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH 190-192                         L-2                                                                              0                                                                                ##STR44##        H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH 161-164                         L-2                                                                              0                                                                                ##STR45##        H  H  -- NHCH.sub.3                                                                         OCH.sub.2 CH.sub.3                                                                  N  180-185                         L-2                                                                              0                                                                                ##STR46##        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N  169-171                         L-2                                                                              0                                                                                ##STR47##        H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N  154-161                         L-2                                                                              0                                                                                ##STR48##        H  H  -- Cl   OCH.sub.3                                                                           CH 167-169                         L-2                                                                              0                                                                                ##STR49##        H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              0                                                                                ##STR50##        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0                                                                                ##STR51##        H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0                                                                                ##STR52##        H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              0                                                                                ##STR53##        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0                                                                                ##STR54##        H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0                                                                                ##STR55##        H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              0 C(CN)CHCN         H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              0 C(CN)CHCN         H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0 C(CN)CHCN         H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 C(CN)CHCN         H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              0 C(CN)CHCN         H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0 C(CN)CHCN         H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 C(CN)CHCN         H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0 CH CHSO.sub.2 N(CH.sub.3).sub.2                                                                 H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              0                                                                                ##STR56##        CH.sub.3                                                                         H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0                                                                                ##STR57##        H  CH.sub.3                                                                         -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 C(CH.sub.2)CH.sub.2 CH.sub.2 CH(NO.sub.2)CH.sub.3                                               H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHCHCH.sub.2 OSO.sub.2 Ph                                                                       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHCHCH.sub.2 OSO.sub.2 CH.sub.3                                                                 H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHCHSCH.sub.3     H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 C(CH.sub.3)CHCH.sub.2 OH                                                                        H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH 185-192                         L-2                                                                              0 C(CH.sub.3)CHCH.sub.2 OH                                                                        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH 189-194                         L-2                                                                              0 C(CH.sub.3)CHCH.sub.2 OH                                                                        H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH 142-149                         L-2                                                                              0 C(CH.sub.3)CHCH.sub.2 OH                                                                        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N  145-150                         L-2                                                                              0 C(CH.sub.3)CHCH.sub.2 OH                                                                        H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N  138-144                         L-2                                                                              0 C(CH.sub.3)CHCH.sub.2 OH                                                                        H  H  -- Cl   OCH.sub.3                                                                           CH 123-130                         L-2                                                                              0 CHCHNO.sub.2      H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              0 CHCHNO.sub.2      H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHCHNO.sub.2      H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH 86-91                           L-2                                                                              0 CHCHNO.sub.2      H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N  182-188                         L-2                                                                              0 CHCHNO.sub.2      H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 CHCHNO.sub.2      H  H  -- Cl   OCH.sub.3                                                                           CH 88-93                           L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.2 CH.sub.3                                                               H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH 214-215                         L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.2 CH.sub.3                                                               H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0 CH C(CN)CO.sub.2 CH.sub.2 CH.sub.3                                                              H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.2 CH.sub.3                                                               H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.2 CH.sub.3                                                               H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.2 CH.sub.3                                                               H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.3                                                                        H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.3                                                                        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.3                                                                        H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.3                                                                        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.3                                                                        H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.3                                                                        H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHC(CN).sub.2     H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              0 CHC(CN).sub.2     H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHC(CN).sub.2     H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHC(CN).sub.2     H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0 CHC(CN).sub.2     H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 CHC(CN).sub.2     H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHC(CO.sub.2 CH.sub.2 CH.sub.3).sub.2                                                           H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              0 CHC(CO.sub.2 CH.sub.2 CH.sub.3).sub.2                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHC(CO.sub.2 CH.sub.2 CH.sub.3).sub.2                                                           H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHC(CO.sub.2 CH.sub.2 CH.sub.3).sub.2                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0 CHC(CO.sub.2 CH.sub.2 CH.sub.3).sub.2                                                           H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 CHC(CO.sub.2 CH.sub.2 CH.sub.3).sub.2                                                           H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHC(CO.sub.2 CH.sub.3).sub.2                                                                    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              0 CHC(CO.sub.2 CH.sub.3).sub.2                                                                    H  H  -- CH.sub.3                                                                           OCH.sub. 3                                                                          CH                                 L-2                                                                              0 CHC(CO.sub.2 CH.sub.3).sub.2                                                                    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHC(CO.sub.2 CH.sub.3).sub.2                                                                    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0 CHC(CO.sub.2 CH.sub.3).sub.2                                                                    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 CHC(CO.sub.2 CH.sub.3).sub.2                                                                    H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHC(NO.sub.2)CO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              0 CHC(NO.sub.2)CO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHC(NO.sub.2)CO.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHC(NO.sub.2)CO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0 CHC(NO.sub.2)CO.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 CHC(NO.sub.2)CO.sub.2 CH.sub.3                                                                  H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              0 C CH              H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              0 C CH              H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0 C CH              H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 C CH              H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              0 C CH              H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0 C CH              H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 C CH              H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              0 C CPh             H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              0 C CPh             H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0 C CPh             H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 C CPh             H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              0 C CPh             H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0 C CPh             H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 C CPh             H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              0 C CCH.sub.3       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              0 C CCH.sub.3       H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0 C CCH.sub.3       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 C CCH.sub.3       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              0 C  CCH.sub.3      H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0 C CCH.sub.3       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 C CCH.sub.3       H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              0 C CCH.sub.2 OC(O)CH.sub.3                                                                       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              0 C CCH.sub.2 OC(O)CH.sub.3                                                                       H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0 C CCH.sub.2 OC(O)CH.sub.3                                                                       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 C CCH.sub.2 OC(O)CH.sub.3                                                                       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              0 C CCH.sub.2 OC(O)CH.sub.3                                                                       H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0 C CCH.sub.2 OC(O)CH.sub.3                                                                       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 C CCH.sub.2 OC(O)CH.sub.3                                                                       H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              0 C CCH.sub.2 OH    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              0 C CCH.sub.2 OH    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0 C CCH.sub.2 OH    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 C CCH.sub.2 OH    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              0 C CCH.sub.2 OH    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0 C CCH.sub.2 OH    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 C CCH.sub.2 OH    H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              0 C CCH.sub.2 Cl    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              0 C CCH.sub.2 Cl    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0 C CCH.sub.2 Cl    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 C CCH.sub.2 Cl    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              0 C CCH.sub.2 Cl    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0 C CCH.sub.2 Cl    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 C CCH.sub.2 Cl    H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              0 C CCH.sub.2 Br    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              0 C  CCH.sub.2 Br   H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0 C CCH.sub.2 Br    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 C CCH.sub.2 Br    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              0 C CCH.sub.2 Br    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0 C CCH.sub.2 Br    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 C CCH.sub.2 Br    H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              0 C CCH.sub.2 CN    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              0 C CCH.sub.2 CN    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0 C  CCH.sub.2 CN   H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 C CCH.sub.2 CN    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              0 C CCH.sub.2 CN    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0 C CCH.sub.2 CN    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 C CCH.sub.2 CN    H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              0 C CCH.sub.2 OCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              0 C CCH.sub.2 OCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0 C CCH.sub.2 OCH.sub.3                                                                           H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 C  CCH.sub.2 OCH.sub.3                                                                          H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              0 C CCH.sub.2 OCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0 C CCH.sub.2 OCH.sub.3                                                                           H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 C CCH.sub.2 OCH.sub.3                                                                           H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub. 3                                                                          CH.sub.3                                                                            N                                  L-2                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              0 C CCH.sub.2 SCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              0 C CCH.sub.2 SCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0 C CCH.sub.2 SCH.sub.3                                                                           H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 C CCH.sub.2 SCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              0 C CCH.sub.2 SCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0 C CCH.sub.2 SCH.sub.3                                                                           H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 C CCH.sub.2 SCH.sub.3                                                                           H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              1 HCCH.sub.2        H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              1 HCCH.sub.2        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              1 HCCH.sub.2        H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              1 HCCH.sub.2        H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              1 HCCH.sub.2        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              1 HCCH.sub.2        H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              1 HCCH.sub.2        H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  -- OCH.sub.3                                                                          OCH.sub. 3                                                                          N                                  L-2                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              1 HCCHPh            H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              1 HCCHPh            H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              1 HCCHPh            H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              1 HCCHPh            H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              1 HCCHPh            H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              1 HCCHPh            H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              1 HCCHPh            H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              1 C CH              H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              1 C CH              H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              1 C CH              H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              1 C CH              H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              1 C CH              H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              1 C CH              H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              1 C CH              H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              1 C CCH.sub.3       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              1 C CCH.sub.3       H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              1 C CCH.sub.3       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              1 C CCH.sub.3       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              1 C CCH.sub.3       H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              1 C  CCH.sub.3      H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              1 C CCH.sub.3       H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              1 C CCH.sub.2 Br    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              1 C CCH.sub.2 Br    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              1 C CCH.sub.2 Br    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              1 C CCH.sub.2 Br    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              1 C CCH.sub.2 Br    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              1 C CCH.sub.2 Br    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              1 C CCH.sub.2 Br    H  H  -- Cl   OCH.sub. 3                                                                          CH                                 L-2                                                                              1 C CPh             H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              1 C CPh             H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              1 C CPh             H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              1 C CPh             H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              1 C CPh             H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              1 C CPh             H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              1 C CPh             H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              1 C CH              CH.sub.3                                                                         H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              1 C CH              CH.sub.3                                                                         H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              1 C CH              CH.sub.3                                                                         H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              1 C CH              CH.sub.3                                                                         H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              1 C CH              CH.sub.3                                                                         H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              1 C CH              CH.sub.3                                                                         H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              1 C CH              CH.sub.3                                                                         H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-2                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              1 C CH              H  CH.sub.3                                                                         -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              1 C CH              H  CH.sub.3                                                                         -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              1 C CH              H  CH.sub.3                                                                         -- OCH.sub.3                                                                          CH.sub.3                                                                            CH                                 L-3                                                                              0 CHCH.sub.2        H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              0 CHCH.sub.2        H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              0 CHCH.sub.2        H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              0 CHCH.sub.2        H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              0 CHCH.sub.2        H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              0 CHCH.sub.2        H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              0 CHCH.sub.2        H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              0 CHCHCN            H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              0 CHCHCN            H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              0 CHCHCN            H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              0 CHCHCN            H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              0 CHCHCN            H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              0 CHCHCN            H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              0 CHCHCN            H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              0 CHCHOCH.sub.3     H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              0 CHCHOCH.sub.3     H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              0 CHCHOCH.sub.3     H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              0 CHCHOCH.sub.3     H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              0 CHCHOCH.sub.3     H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              0 CHCHOCH.sub.3     H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              0 CHCHOCH.sub.3     H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub. 3                                                                          CH                                 L-3                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              0 CHCHPh            H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              0 CHCHPh            H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              0 CHCHPh            H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              0 CHCHPh            H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              0 CHCHPh            H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              0 CHCHPh            H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              0 CHCHPh            H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              0 C(CH.sub.3)CHPh   H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              0 C(CH.sub.3)CHPh   H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              0 C(CH.sub.3)CHPh   H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              0 C(CH.sub.3)CHPh   H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              0 C(CH.sub.3)CHPh   H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              0 C(CH.sub.3)CHPh   H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              0 C(CH.sub.3)CHPh   H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              0                                                                                ##STR58##        H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              0                                                                                ##STR59##        H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              0                                                                                ##STR60##        H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              0                                                                                ##STR61##        H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              0                                                                                ##STR62##        H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              0                                                                                ##STR63##        H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              0                                                                                ##STR64##        H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              0                                                                                ##STR65##        H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              0                                                                                ##STR66##        H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              0                                                                                ##STR67##        H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              0                                                                                ##STR68##        H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              0                                                                                ##STR69##        H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              0                                                                                ##STR70##        H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              0                                                                                ##STR71##        H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              0                                                                                ##STR72##        H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              0                                                                                ##STR73##        H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                L-3                                        CH                                    0                                                                                ##STR74##        H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              0                                                                                ##STR75##        H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              0                                                                                ##STR76##        H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              0                                                                                ##STR77##        H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              0                                                                                ##STR78##        H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              0 C(CN)CHCN         H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              0 C(CN)CHCN         H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              0 C(CN)CHCN         H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              0 C(CN)CHCN         H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              0 C(CN)CHCN         H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              0 C(CN)CHCN         H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              0 C(CN)CHCN         H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              0 CHCHSO.sub.2 N(CH.sub.3 ).sub.2                                                                 H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              0                                                                                ##STR79##        CH.sub.3                                                                         H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              0                                                                                ##STR80##        H  CH.sub.3                                                                         CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              0 C(CH.sub.2)CH.sub.2 CH.sub.2 CH(NO.sub.2)CH.sub.3                                               H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              0 CHCHCH.sub.2 OSO.sub.2 Ph                                                                       H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              0 CHCHCH.sub.2 OSO.sub.2 CH.sub.3                                                                 H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              0 CHCHSCH.sub.3     H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              0 C CH              H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              0 C CH.sub.3        H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              0 C CH              H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              0 C CH              H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              0 C CH              H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              0 C CH              H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              0 C  CH             H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              0 C CPh             H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              0 C CPh             H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              0 C CPh             H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              0 C CPh             H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              0 C CPh             H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              0 C CPh             H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              0 C CPh             H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              0 C CCH.sub.3       H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              0 C CCH.sub.3       H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              0 C CCH.sub.3       H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              0 C CCH.sub.3       H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              0 C CCH.sub.3       H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              0 C CCH.sub.3       H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              0 C CCH.sub.3       H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              0 C CCH.sub.2 OC(O)CH.sub.3                                                                       H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              0 C CCH.sub.2 OC(O)CH.sub.3                                                                       H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              0 C  CCH.sub.2 OC(O)CH.sub.3                                                                      H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              0 C CCH.sub.2 OC(O)CH.sub.3                                                                       H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              0 C CCH.sub.2 OC(O)CH.sub.3                                                                       H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              0 C CCH.sub.2 OC(O)CH.sub.3                                                                       H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              0 C CCH.sub.2 OC(O)CH.sub.3                                                                       H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              0 C CCH.sub.2 OH    H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              0 C CCH.sub.2 OH    H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              0 C CCH.sub.2 OH    H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              0 C  CCH.sub.2 OH   H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              0 C CCH.sub.2 OH    H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              0 C CCH.sub.2 OH    H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              0 C CCH.sub.2 OH    H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              0 C CCH.sub.2 Cl    H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              0 C CCH.sub.2 Cl    H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              0 C CCH.sub.2 Cl    H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              0 C CCH.sub.2 Cl    H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              0 C CCH.sub.2 Cl    H  H  CH.sub.3                                                                         CH.sub. 3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              0 C CCH.sub.2 Cl    H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              0 C CCH.sub.2 Cl    H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              0 C CCH.sub.2 Br    H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              0 C CCH.sub.2 Br    H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              0 C CCH.sub.2 Br    H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              0 C CCH.sub.2 Br    H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              0 C CCH.sub.2 Br    H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              0 C CCH.sub.2 Br    H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              0 C CCH.sub.2 Br    H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              0 C CCH.sub.2 CN    H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              0 C CCH.sub.2 CN    H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              0 C CCH.sub.2 CN    H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              0 C CCH.sub.2 CN    H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              0 C CCH.sub.2 CN    H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              0 C CCH.sub.2 CN    H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              0 C CCH.sub.2 CN    H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              0 C CCH.sub.2 OCH.sub.3                                                                           H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              0 C CCH.sub.2 OCH.sub.3                                                                           H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              0 C CCH.sub.2 OCH.sub.3                                                                           H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              0 C CCH.sub.2 OCH.sub.3                                                                           H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              0 C CCH.sub.2 OCH.sub.3                                                                           H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              0 C CCH.sub.2 OCH.sub.3                                                                           H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              0 C CCH.sub.2 OCH.sub.3                                                                           H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              0 C CCH.sub.2 SCH.sub.3                                                                           H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              0 C  CCH.sub.2 SCH.sub.3                                                                          H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              0 C CCH.sub.2 SCH.sub.3                                                                           H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              0 C CCH.sub.2 SCH.sub.3                                                                           H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              0 C CCH.sub.2 SCH.sub.3                                                                           H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              0 C CCH.sub.2 SCH.sub.3                                                                           H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              0 C CCH.sub.2 SCH.sub.3                                                                           H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              1 HCCH.sub.2        H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              1 HCCH.sub.2        H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              1 HCCH.sub.2        H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              1 HCCH.sub.2        H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              1 HCCH.sub.2        H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              1 HCCH.sub.2        H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              1 HCCH.sub.2        H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              1 HCC(CH.sub. 3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                             H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              1 HCCHPh            H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              1 HCCHPh            H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              1 HCCHPh            H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              1 HCCHPh            H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              1 HCCHPh            H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              1 HCCHPh            H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              1 HCCHPh            H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              1 HCCHCH.sub.3      H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              1 HCCHCH.sub.3      H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              1 HCCHCH.sub.3      H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              1 HCCHCH.sub.3      H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              1 HCCHCH.sub.3      H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              1 HCCHCH.sub.3      H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              1 HCCHCH.sub.3      H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              1 C CH              H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              1 C CH              H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              1 C CH              H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              1 C CH              H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              1 C  CH             H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              1 C CH              H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              1 C CH              H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              1 C CCH.sub.3       H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              1 C CCH.sub.3       H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              1 C CCH.sub.3       H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              1 C CCH.sub.3       H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              1 C CCH.sub.3       H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              1 C CCH.sub.3       H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              1 C  CCH.sub.3      H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              1 C CCH.sub.2 Br    H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              1 C CCH.sub.2 Br    H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              1 C CCH.sub.2 Br    H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              1 C CCH.sub.2 Br    H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              1 C CCH.sub.2 Br    H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              1 C CCH.sub.2 Br    H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              1 C CCH.sub.2 Br    H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              1 C  CPh            H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              1 C CPh             H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              1 C CPh             H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              1 C CPh             H  H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              1 C CPh             H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              1 C CPh             H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              1 C CPh             H  H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              1 CHCH.sub. 2       CH.sub.3                                                                         H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              1 C CH              CH.sub.3                                                                         H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              1 C CH              CH.sub.3                                                                         H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              1 C CH              CH.sub.3                                                                         H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              1 C CH              CH.sub.3                                                                         H  CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              1 C CH              CH.sub.3                                                                         H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              1 C CH              CH.sub.3                                                                         H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              1 C  CH             CH.sub.3                                                                         H  CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-3                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-3                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         CH.sub.3                                                                         CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-3                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-3                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         CH.sub.3                                                                         Cl   OCH.sub.3                                                                           CH                                 L-3                                                                              1 C CH              H  CH.sub.3                                                                         CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-3                                                                              1 C CH              H  CH.sub.3                                                                         CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-3                                                                              1 C CH              H  CH.sub.3                                                                         CH.sub.3                                                                         OCH.sub.3                                                                          CH.sub.3                                                                            CH                                 L-3                                                                              0 CHCHCH.sub.3      H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           N  159-162                         L-3                                                                              0 CHCHCH.sub.3      H  H  CH.sub.3                                                                         CH.sub.3                                                                           OCH.sub.3                                                                           CH 155-158                         L-3                                                                              0 CHCHCH.sub.3      H  H  CH.sub.3                                                                         OCH.sub.3                                                                          OCH.sub.3                                                                           CH 154-156                         L-4                                                                              0 CHCH.sub.2        H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              0 CHCH.sub.2        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              0 CHCH.sub.2        H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              0 CHCH.sub.2        H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              0 CHCH.sub.2        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              0 CHCH.sub.2        H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              0 CHCH.sub.2        H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              0 CHCHCN            H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              0 CHCHCN            H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              0 CHCHCN            H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              0 CHCHCN            H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              0 CHCHCN            H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              0 CHCHCN            H  H  -- OCH.sub.3                                                                          OCH.sub.                                                                            N                                  L-4                                                                              0 CHCHCN            H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              0 CHCHOCH.sub.3     H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              0 CHCHOCH.sub.3     H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              0 CHCHOCH.sub.3     H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              0 CHCHOCH.sub.3     H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              0 CHCHOCH.sub.3     H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              0 CHCHOCH.sub.3     H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              0 CHCHOCH.sub.3     H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              0 CHCHPh            H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              0 CHCHPh            H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              0 CHCHPh            H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              0 CHCHPh            H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              0 CHCHPh            H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              0 CHCHPh            H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              0 CHCHPh            H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              0 C(CH.sub.3)CHPh   H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              0 C(CH.sub.3)CHPh   H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              0 C(CH.sub.3)CHPh   H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              0 C(CH.sub.3)CHPh   H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              0 C(CH.sub.3)CHPh   H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              0 C(CH.sub.3)CHPh   H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              0 C(CH.sub.3)CHPh   H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              0                                                                                ##STR81##        H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              0                                                                                ##STR82##        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              0                                                                                ##STR83##        H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              0                                                                                ##STR84##        H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              0                                                                                ##STR85##        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              0                                                                                ##STR86##        H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              0                                                                                ##STR87##        H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              0                                                                                ##STR88##        H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              0                                                                                ##STR89##        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              0                                                                                ##STR90##        H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              0                                                                                ##STR91##        H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              0                                                                                ##STR92##        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              0                                                                                ##STR93##        H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              0                                                                                ##STR94##        H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              0                                                                                ##STR95##        H  H  -- CH.sub.3                                                                           CH.sub.3                                 L-4                                        CH                                    0                                                                                ##STR96##        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              0                                                                                ##STR97##        H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              0                                                                                ##STR98##        H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              0                                                                                ##STR99##        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              0                                                                                ##STR100##       H  H  -- OCH.sub. 3                                                                         OCH.sub.3                                                                           N                                  L-4                                                                              0                                                                                ##STR101##       H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              0 C(CN)CHCN         H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              0 C(CN)CHCN         H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              0 C(CN)CHCN         H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              0 C(CN)CHCN         H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              0 C(CN)CHCN         H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              0 C(CN)CHCN         H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              0 C(CN)CHCN         H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              0 CHCHSO.sub.2 N(CH.sub.3 ).sub.2                                                                 H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                L-4                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              0                                                                                ##STR102##       CH.sub.3                                                                         H  -- OCH.sub. 3                                                                         OCH.sub.3                                                                           CH                                 L-4                                                                              0                                                                                ##STR103##       H  CH.sub.3                                                                         -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              0 C(CH.sub.2)CH.sub.2 CH.sub.2 CH(NO.sub.2)CH.sub.3                                               H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              0 CHCHCH.sub.2 OSO.sub.2 Ph                                                                       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              0 CHCHCH.sub.2 OSO.sub.2 CH.sub.3                                                                 H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              0 CHCHSCH.sub.3     H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              0 C CH              H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              0 C CH              H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              0 C CH              H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              0 C CH              H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              0 C  CH             H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              0 C CH              H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              0 C CH              H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              0 C CPh             H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              0 C CPh             H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              0 C CPh             H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              0 C CPh             H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              0 C CPh             H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              0 C CPh             H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              0 C  CPh            H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              0 C CCH.sub.3       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              0 C CCH.sub.3       H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              0 C CCH.sub.3       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              0 C CCH.sub.3       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              0 C CCH.sub.3       H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              0 C CCH.sub.3       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              0 C CCH.sub.3       H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              0 C CCH.sub.2 OC(O)CH.sub. 3                                                                      H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              0 C CCH.sub.2 OC(O)CH.sub.3                                                                       H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              0 C CCH.sub.2 OC(O)CH.sub.3                                                                       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              0 C CCH.sub.2 OC(O)CH.sub.3                                                                       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              0 C CCH.sub.2 OC(O)CH.sub.3                                                                       H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              0 C CCH.sub.2 OC(O)CH.sub.3                                                                       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              0 C CCH.sub.2 OC(O)CH.sub.3                                                                       H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              0 C CCH.sub.2 OH    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              0 C CCH.sub.2 OH    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              0 C CCH.sub.2 OH    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              0 C CCH.sub.2 OH    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              0 C CCH.sub.2 OH    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              0 C CCH.sub.2 OH    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              0 C CCH.sub.2 OH    H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              0 C CCH.sub.2 Cl    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              0 C CCH.sub.2 Cl    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              0 C CCH.sub.2 Cl    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              0 C CCH.sub.2 Cl    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              0 C CCH.sub.2 Cl    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              0 C CCH.sub.2 Cl    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              0 C CCH.sub.2 Cl    H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              0 C CCH.sub.2 Br    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              0 C CCH.sub.2 Br    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              0 C CCH.sub.2 Br    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              0 C CCH.sub.2 Br    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              0 C  CCH.sub.2 Br   H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              0 C CCH.sub.2 Br    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              0 C CCH.sub.2 Br    H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              0 C CCH.sub.2 CN    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              0 C CCH.sub.2 CN    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              0 C CCH.sub.2 CN    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              0 C CCH.sub.2 CN    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              0 C CCH.sub.2 CN    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              0 C  CCH.sub.2 CN   H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              0 C CCH.sub.2 CN    H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              0 C CCH.sub.2 OCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              0 C CCH.sub.2 OCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              0 C CCH.sub.2 OCH.sub.3                                                                           H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              0 C CCH.sub.2 OCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              0 C CCH.sub.2 OCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              0 C CCH.sub.2 OCH.sub.3                                                                           H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              0 C  CCH.sub.2 OCH.sub.3                                                                          H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              0 C CCH.sub.2 SCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              0 C CCH.sub.2 SCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              0 C CCH.sub.2 SCH.sub.3                                                                           H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              0 C CCH.sub.2 SCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              0 C CCH.sub.2 SCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              0 C CCH.sub.2 SCH.sub.3                                                                           H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              0 C CCH.sub.2 SCH.sub.3                                                                           H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              1 HCCH.sub.2        H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              1 HCCH.sub.2        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              1 HCCH.sub.2        H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              1 HCCH.sub.2        H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              1 HCCH.sub.2        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              1 HCCH.sub.2        H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              1 HCCH.sub.2        H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub. 2 CHC(CH.sub.3).sub.2                                             H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              1 HCCHPh            H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              1 HCCHPh            H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              1 HCCHPh            H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              1 HCCHPh            H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              1 HCCHPh            H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              1 HCCHPh            H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              1 HCCHPh            H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              1 HCCHCH.sub.3      H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              1 HCCHCH.sub.3      H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              1 HCCHCH.sub.3      H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              1 HCCHCH.sub.3      H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              1 HCCHCH.sub.3      H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              1 HCCHCH.sub.3      H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              1 HCCHCH.sub.3      H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              1 C CH              H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              1 C CH              H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              1 C  CH             H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              1 C CH              H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              1 C CH              H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              1 C CH              H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              1 C CH              H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              1 C CCH.sub.3       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              1 C CCH.sub.3       H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              1 C CCH.sub.3       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              1 C CCH.sub.3       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              1 C  CCH.sub.3      H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              1 C CCH.sub.3       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              1 C CCH.sub.3       H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              1 C CCH.sub.2 Br    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              1 C CCH.sub.2 Br    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              1 C CCH.sub.2 Br    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              1 C CCH.sub.2 Br    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              1 C CCH.sub.2 Br    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              1 C CCH.sub.2 Br    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              1 C CCH.sub.2 Br    H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              1 C CPh             H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              1 C CPh             H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              1 C CPh             H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              1 C CPh             H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              1 C CPh             H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              1 C CPh             H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              1 C CPh             H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              1 C CH              CH.sub.3                                                                         H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              1 C CH              CH.sub.3                                                                         H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              1 C CH              CH.sub.3                                                                         H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              1 C CH              CH.sub.3                                                                         H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              1 C  CH             CH.sub.3                                                                         H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              1 C CH              CH.sub.3                                                                         H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              1 C CH              CH.sub.3                                                                         H  -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-4                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-4                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-4                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-4                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         -- Cl   OCH.sub.3                                                                           CH                                 L-4                                                                              1 C CH              H  CH.sub.3                                                                         -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-4                                                                              1 C CH              H  CH.sub.3                                                                         -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-4                                                                              1 C CH              H  CH.sub.3                                                                         -- OCH.sub.3                                                                          CH.sub.3                                                                            CH                                 L-5                                                                              0 CHCH.sub.2        H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              0 CHCH.sub.2        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              0 CHCH.sub.2        H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              0 CHCH.sub.2        H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              0 CHCH.sub.2        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              0 CHCH.sub.2        H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              0 CHCH.sub.2        H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub. 3                                                                          CH                                 L-5                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              0 CHCHCN            H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              0 CHCHCN            H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              0 CHCHCN            H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              0 CHCHCN            H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              0 CHCHCN            H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              0 CHCHCN            H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              0 CHCHCN            H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              0 CHCHOCH.sub.3     H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              0 CHCHOCH.sub.3     H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              0 CHCHOCH.sub.3     H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              0 CHCHOCH.sub.3     H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              0 CHCHOCH.sub.3     H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              0 CHCHOCH.sub.3     H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              0 CHCHOCH.sub.3     H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              0 CHCHPh            H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              0 CHCHPh            H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              0 CHCHPh            H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              0 CHCHPh            H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              0 CHCHPh            H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              0 CHCHPh            H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              0 CHCHPh            H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              0 C(CH.sub.3)CHPh   H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              0 C(CH.sub.3)CHPh   H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              0 C(CH.sub.3)CHPh   H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              0 C(CH.sub.3)CHPh   H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              0 C(CH.sub.3)CHPh   H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              0 C(CH.sub.3)CHPh   H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              0 C(CH.sub.3)CHPh   H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              0                                                                                ##STR104##       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              0                                                                                ##STR105##       H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              0                                                                                ##STR106##       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              0                                                                                ##STR107##       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              0                                                                                ##STR108##       H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              0                                                                                ##STR109##       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              0                                                                                ##STR110##       H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              0                                                                                ##STR111##       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              0                                                                                ##STR112##       H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              0                                                                                ##STR113##       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              0                                                                                ##STR114##       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              0                                                                                ##STR115##       H  H  -- CH.sub. 3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              0                                                                                ##STR116##       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              0                                                                                ##STR117##       H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              0                                                                                ##STR118##       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              0                                                                                ##STR119##       H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              0                                                                                ##STR120##       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              0                                                                                ##STR121##       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              0                                                                                ##STR122##       H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              0                                                                                ##STR123##       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              0                                                                                ##STR124##       H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              0 C(CN)CHCN         H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              0 C(CN)CHCN         H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              0 C(CN)CHCN         H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              0 C(CN)CHCN         H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              0 C(CN)CHCN         H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              0 C(CN)CHCN         H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              0 C(CN)CHCN         H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              0                                                                                ##STR125##       CH.sub.3                                                                         H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              0                                                                                ##STR126##       H  CH.sub.3                                                                         -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              0 C(CH.sub.2)CH.sub.2 CH.sub.2 CH(NO.sub.2)CH.sub.3                                               H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              0 CHCHCH.sub.2 OSO.sub.2 Ph                                                                       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              0 CHCHCH.sub.2 OSO.sub.2 CH.sub.3                                                                 H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              0 CHCHSCH.sub.3     H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              0 C CH              H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              0 C CH              H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              0 C CH              H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              0 C CH              H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              0 C CH              H  H  -- CH.sub. 3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              0 C CH              H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              0 C CH              H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              0 C CPh             H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              0 C CPh             H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              0 C CPh             H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              0 C CPh             H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              0 C CPh             H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              0 C CPh             H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              0 C CPh             H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              0 C CCH.sub.3       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              0 C CCH.sub.3       H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              0 C CCH.sub.3       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              0 C CCH.sub.3       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              0 C CCH.sub.3       H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              0 C CCH.sub.3       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              0 C CCH.sub.3       H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              0 C CCH.sub.2 OC(O)CH.sub.3                                                                       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              0 C CCH.sub.2 OC(O)CH.sub.3                                                                       H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              0 C CCH.sub.2 OC(O)CH.sub.3                                                                       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              0 C CCH.sub.2 OC(O)CH.sub.3                                                                       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              0 C CCH.sub.2 OC(O)CH.sub.3                                                                       H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              0 C CCH.sub.2 OC(O)CH.sub.3                                                                       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              0 C CCH.sub.2 OC(O)CH.sub.3                                                                       H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              0 C CCH.sub.2 OH    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              0 C CCH.sub.2 OH    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              0 C  CCH.sub.2 OH   H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              0 C CCH.sub.2 OH    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              0 C CCH.sub.2 OH    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              0 C CCH.sub.2 OH    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              0 C CCH.sub.2 OH    H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              0 C CCH.sub.2 Cl    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              0 C CCH.sub.2 Cl    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              0 C CCH.sub.2 Cl    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              0 C CCH.sub.2 Cl    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              0 C CCH.sub.2 Cl    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              0 C CCH.sub.2 Cl    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              0 C CCH.sub.2 Cl    H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              0 C CCH.sub.2 Br    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              0 C CCH.sub.2 Br    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              0 C CCH.sub.2 Br    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              0 C CCH.sub.2 Br    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              0 C CCH.sub.2 Br    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              0 C CCH.sub.2 Br    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              0 C CCH.sub.2 Br    H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              0 C CCH.sub.2 CN    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              0 C CCH.sub.2 CN    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              0 C CCH.sub.2 CN    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              0 C CCH.sub.2 CN    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              0 C CCH.sub.2 CN    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              0 C CCH.sub.2 CN    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              0 C  CCH.sub.2 CN   H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              0 C CCH.sub.2 OCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              0 C CCH.sub.2 OCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              0 C CCH.sub.2 OCH.sub.3                                                                           H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              0 C CCH.sub.2 OCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              0 C CCH.sub.2 OCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              0 C CCH.sub.2 OCH.sub.3                                                                           H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              0 C CCH.sub.2 OCH.sub.3                                                                           H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              0 C  CCH.sub.2 SCH.sub.3                                                                          H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              0 C CCH.sub.2 SCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              0 C CCH.sub.2 SCH.sub.3                                                                           H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              0 C CCH.sub.2 SCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              0 C CCH.sub.2 SCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              0 C CCH.sub.2 SCH.sub.3                                                                           H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              0 C CCH.sub.2 SCH.sub.3                                                                           H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              1 HCCH.sub.2        H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              1 HCCH.sub.2        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              1 HCCH.sub.2        H  H  -- OCH.sub. 3                                                                         OCH.sub.3                                                                           CH                                 L-5                                                                              1 HCCH.sub.2        H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              1 HCCH.sub.2        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              1 HCCH.sub.2        H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              1 HCCH.sub.2        H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              1 HCCHPh            H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              1 HCCHPh            H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              1 HCCHPh            H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              1 HCCHPh            H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              1 HCCHPh            H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              1 HCCHPh            H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              1 HCCHPh            H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              1 HCCHCH.sub.3      H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              1 HCCHCH.sub.3      H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              1 HCCHCH.sub.3      H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              1 HCCHCH.sub.3      H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              1 HCCHCH.sub.3      H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              1 HCCHCH.sub.3      H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              1 HCCHCH.sub.3      H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              1 C CH              H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              1 C CH              H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              1 C CH              H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              1 C  CH             H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              1 C CH              H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              1 C CH              H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              1 C CH              H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              1 C CCH.sub.3       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              1 C CCH.sub.3       H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              1 C CCH.sub.3       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              1 C CCH.sub.3       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              1 C CCH.sub.3       H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              1 C  CCH.sub.3      H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              1 C CCH.sub.3       H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              1 C CCH.sub.2 Br    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              1 C CCH.sub.2 Br    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              1 C CCH.sub.2 Br    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              1 C CCH.sub.2 Br    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              1 C CCH.sub.2 Br    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              1 C CCH.sub.2 Br    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              1 C C CH.sub.2 Br   H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              1 C CPh             H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              1 C CPh             H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              1 C CPh             H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              1 C CPh             H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              1 C CPh             H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              1 C CPh             H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              1 C CPh             H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              1 C CH              CH.sub.3                                                                         H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              1 C CH              CH.sub.3                                                                         H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              1 C CH              CH.sub.3                                                                         H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              1 C CH              CH.sub.3                                                                         H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              1 C CH              CH.sub.3                                                                         H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              1 C  CH             CH.sub.3                                                                         H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              1 C CH              CH.sub.3                                                                         H  -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-5                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-5                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-5                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-5                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         -- Cl   OCH.sub.3                                                                           CH                                 L-5                                                                              1 C CH              H  CH.sub.3                                                                         -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-5                                                                              1 C CH              H  CH.sub.3                                                                         -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-5                                                                              1 C CH              H  CH.sub.3                                                                         -- OCH.sub.3                                                                          CH.sub.3                                                                            CH                                 L-6                                                                              0 CHCH.sub.2        H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              0 CHCH.sub.2        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              0 CHCH.sub.2        H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              0 CHCH.sub.2        H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              0 CHCH.sub.2        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              0 CHCH.sub.2        H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              0 CHCH.sub.2        H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              0 CHCHCN            H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              0 CHCHCN            H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              0 CHCHCN            H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              0 CHCHCN            H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              0 CHCHCN            H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              0 CHCHCN            H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              0 CHCHCN            H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              0 CHCHOCH.sub.3     H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              0 CHCHOCH.sub.3     H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              0 CHCHOCH.sub.3     H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              0 CHCHOCH.sub.3     H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              0 CHCHOCH.sub.3     H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              0 CHCHOCH.sub.3     H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              0 CHCHOCH.sub.3     H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              0 CHCHBr            H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              0 CHCHBr            H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              0 CHCHBr            H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              0 CHCHBr            H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              0 CHCHBr            H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              0 CHCHBr            H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              0 CHCHBr            H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              0 CHCHCF.sub.3      H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              0 CHCHCF.sub.3      H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              0 CHCHCF.sub.3      H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              0 CHCHCF.sub.3      H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              0 CHCHCF.sub.3      H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              0 CHCHCF.sub.3      H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              0 CHCHCF.sub.3      H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              0 C(CH.sub. 3)CHOCH.sub.3                                                                         H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              0 CHCHPh            H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              0 CHCHPh            H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              0 CHCHPh            H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              0 CHCHPh            H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              0 CHCHPh            H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              0 CHCHPh            H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              0 CHCHPh            H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              0 C(CH.sub.3)CHPh   H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              0 C(CH.sub.3)CHPh   H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              0 C(CH.sub.3)CHPh   H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              0 C(CH.sub.3)CHPh   H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              0 C(CH.sub.3)CHPh   H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              0 C(CH.sub.3)CHPh   H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              0 C(CH.sub.3)CHPh   H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              0                                                                                ##STR127##       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              0                                                                                ##STR128##       H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              0                                                                                ##STR129##       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              0                                                                                ##STR130##       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              0                                                                                ##STR131##       H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              0                                                                                ##STR132##       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              0                                                                                ##STR133##       H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              0                                                                                ##STR134##       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              0                                                                                ##STR135##       H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              0                                                                                ##STR136##       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              0                                                                                ##STR137##       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              0                                                                                ##STR138##       H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              0                                                                                ##STR139##       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              0                                                                                ##STR140##       H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              0                                                                                ##STR141##       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              0                                                                                ##STR142##       H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              0                                                                                ##STR143##       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              0                                                                                ##STR144##       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              0                                                                                ##STR145##       H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              0                                                                                ##STR146##       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              0                                                                                ##STR147##       H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              0 C(CN)CHCN         H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              0 C(CN)CHCN         H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              0 C(CN)CHCN         H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              0 C(CN)CHCN         H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              0 C(CN)CHCN         H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              0 C(CN)CHCN         H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              0 C(CN)CHCN         H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              0                                                                                ##STR148##       CH.sub.3                                                                         H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              0                                                                                ##STR149##       H  CH.sub.3                                                                         -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              0 C(CH.sub.2)CH.sub.2 CH.sub.2 CH(NO.sub.2)CH.sub.3                                               H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              0 CHCHCH.sub.2 OSO.sub.2 Ph                                                                       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              0 CHCHCH.sub.2 OSO.sub.2 CH.sub.3                                                                 H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              0 CHCHSCH.sub.3     H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              0 C CH              H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              0 C CH              H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              0 C CH              H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              0 C CH              H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              0 C CH              H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              0 C CH              H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              0 C CH              H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              0 C CPh             H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              0 C CPh             H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              0 C CPh             H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              0 C CPh             H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              0 C CPh             H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              0 C CPh             H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              0 C CPh             H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              0 C  CCH.sub.3      H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              0 C CCH.sub.3       H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              0 C CCH.sub.3       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              0 C CCH.sub.3       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              0 C CCH.sub.3       H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              0 C CCH.sub.3       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              0 C CCH.sub.3       H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              0 C CCH.sub.2 OC(O)CH.sub.3                                                                       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              0 C CCH.sub.2 OC(O)CH.sub.3                                                                       H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              0 C CCH.sub.2 OC(O)CH.sub.3                                                                       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              0 C CCH.sub.2 OC(O)CH.sub.3                                                                       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              0 C CCH.sub.2 OC(O)CH.sub.3                                                                       H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              0 C CCH.sub.2 OC(O)CH.sub.3                                                                       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              0 C CCH.sub.2 OC(O)CH.sub.3                                                                       H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              0 C CCH.sub.2 OH    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              0 C CCH.sub.2 OH    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              0 C CCH.sub.2 OH    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              0 C CCH.sub.2 OH    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              0 C CCH.sub.2 OH    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              0 C CCH.sub.2 OH    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              0 C CCH.sub.2 OH    H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              0 C CCH.sub.2 Cl    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              0 C CCH.sub.2 Cl    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              0 C CCH.sub.2 Cl    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              0 C CCH.sub.2 Cl    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              0 C  CCH.sub.2 Cl   H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              0 C CCH.sub.2 Cl    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              0 C CCH.sub.2 Cl    H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              0 C CCH.sub.2 Br    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              0 C CCH.sub.2 Br    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              0 C CCH.sub.2 Br    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              0 C CCH.sub.2 Br    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              0 C CCH.sub.2 Br    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              0 C C CH.sub.2 Br   H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              0 C CCH.sub.2 Br    H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              0 C CCH.sub.2 CN    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              0 C CCH.sub.2 CN    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              0 C CCH.sub.2 CN    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              0 C CCH.sub.2 CN    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              0 C CCH.sub.2 CN    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              0 C CCH.sub.2 CN    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              0 C CCH.sub. 2 CN   H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              0 C CCH.sub.2 OCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              0 C CCH.sub.2 OCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              0 C CCH.sub.2 OCH.sub.3                                                                           H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              0 C CCH.sub.2 OCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              0 C CCH.sub.2 OCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              0 C CCH.sub.2 OCH.sub.3                                                                           H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              0 C CCH.sub.2 OCH.sub.3                                                                           H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              0 C  CCH.sub.2 OSO.sub.2 CH.sub.3                                                                 H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              0 C CCH.sub.2 SCH.sub.3                                                                           H  H  -- CH.sub. 3                                                                          CH.sub.3                                                                            CH                                 L-6                                                                              0 C CCH.sub.2 SCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              0 C CCH.sub.2 SCH.sub.3                                                                           H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              0 C CCH.sub.2 SCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              0 C CCH.sub.2 SCH.sub.3                                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              0 C CCH.sub.2 SCH.sub.3                                                                           H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              0 C CCH.sub.2 SCH.sub.3                                                                           H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              1 HCCH.sub.2        H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              1 HCCH.sub.2        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              1 HCCH.sub.2        H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              1 HCCH.sub.2        H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              1 HCCH.sub.2        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              1 HCCH.sub.2        H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              1 HCCH.sub.2        H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              1 BrCCH.sub.2       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              1 BrCCH.sub.2       H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              1 BrCCH.sub.2       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              1 BrCCH.sub.2       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              1 BrCCH.sub.2       H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              1 BrCCH.sub.2       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              1 BrCCH.sub.2       H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              1 HCC(CH.sub.3).sub. 2                                                                            H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              1 HCC(CH.sub.3 )CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                             H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              1 HCCHPh            H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              1 HCCHPh            H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              1 HCCHPh            H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              1 HCCHPh            H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              1 HCCHPh            H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              1 HCCHPh            H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              1 HCCHPh            H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              1 HCCHCH.sub.3      H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              1 HCCHCH.sub.3      H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              1 HCCHCH.sub.3      H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              1 HCCHCH.sub.3      H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              1 HCCHCH.sub.3      H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              1 HCCHCH.sub.3      H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              1 HCCHCH.sub.3      H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              1 HCCHCH.sub.2 Br   H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              1 HCCHCH.sub.2 Br   H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              1 HCCHCH.sub.2 Br   H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              1 HCCHCH.sub.2 Br   H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              1 HCCHCH.sub.2 Br   H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              1 HCCHCH.sub.2 Br   H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              1 HCCHCH.sub.2 Br   H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              1 C CH              H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              1 C CH              H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              1 C CH              H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              1 C CH              H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              1 C CH              H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              1 C CH              H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              1 C CH              H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              1 C CCH.sub.3       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              1 C CCH.sub.3       H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              1 C CCH.sub.3       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              1 C CCH.sub.3       H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              1 C CCH.sub.3       H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              1 C CCH.sub.3       H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              1 C CCH.sub.3       H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              1 C CCH.sub.2 Br    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              1 C CCH.sub.2 Br    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              1 C CCH.sub.2 Br    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              1 C CCH.sub.2 Br    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              1 C CCH.sub.2 Br    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              1 C CCH.sub.2 Br    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              1 C CCH.sub.2 Br    H  H  -- Cl   OCH.sub. 3                                                                          CH                                 L-6                                                                              1 C CPh             H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              1 C CPh             H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              1 C CPh             H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              1 C CPh             H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              1 C CPh             H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              1 C CPh             H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              1 C CPh             H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              1 C CH              CH.sub.3                                                                         H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              1 C CH              CH.sub.3                                                                         H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              1 C CH              CH.sub.3                                                                         H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              1 C CH              CH.sub.3                                                                         H  -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              1 C CH              CH.sub.3                                                                         H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              1 C CH              CH.sub.3                                                                         H  -- OCH.sub. 3                                                                         OCH.sub.3                                                                           N                                  L-6                                                                              1 C CH              CH.sub.3                                                                         H  -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-6                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-6                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         -- CH.sub.3                                                                           CH.sub.3                                                                            N                                  L-6                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-6                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         -- Cl   OCH.sub.3                                                                           CH                                 L-6                                                                              1 C CH              H  CH.sub.3                                                                         -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-6                                                                              1 C CH              H  CH.sub.3                                                                         -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-6                                                                              1 C CH              H  CH.sub.3                                                                         -- OCH.sub.3                                                                          CH.sub.3                                                                            CH                                 L-2                                                                              0 C(CH.sub.3)CHCH.sub.2 OH                                                                        H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH 185-192                         L-2                                                                              0 C(CH.sub.3)CHCH.sub.2 OH                                                                        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH 189-194                         L-2                                                                              0 C(CH.sub.3)CHCH.sub.2 OH                                                                        H  H  -- OCH.sub.3                                                                          OH.sub.3                                                                            CH 142-149                         L-2                                                                              0 C(CH.sub.3)CHCH.sub.2 OH                                                                        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N  145-150                         L-2                                                                              0 C(CH.sub.3)CHCH.sub.2 OH                                                                        H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N  138-144                         L-2                                                                              0 C(CH.sub.3)CHCH.sub.2 OH                                                                        H  H  -- Cl   OCH.sub.3                                                                           CH 123-130                         L-2                                                                              0 CHC(CN).sub.2     H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              0 CHC(CN).sub.2     H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHC(CN).sub.2     H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHC(CN).sub.2     H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0 CHC(CN).sub.2     H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 CHC(CN).sub.2     H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.2 CH.sub.3                                                               H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH 214-215                         L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.2 CH.sub.3                                                               H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.2 CH.sub.3                                                               H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.2 CH.sub.3                                                               H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.2 CH.sub.3                                                               H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.2 CH.sub.3                                                               H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHC(CO.sub.2 CH.sub.2 CH.sub.3).sub.2                                                           H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              0 CHC(CO.sub.2 CH.sub.2 CH.sub.3).sub.2                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHC(CO.sub.2 CH.sub.2 CH.sub.3).sub.2                                                           H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHC(CO.sub.2 CH.sub.2 CH.sub.3).sub.2                                                           H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0 CHC(CO.sub.2 CH.sub.2 CH.sub.3).sub. 2                                                          H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 CHC(CO.sub.2 CH.sub.2 CH.sub.3).sub.2                                                           H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.3                                                                        H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.3                                                                        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.3                                                                        H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.3                                                                        H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.3                                                                        H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.3                                                                        H  H  -- Cl   OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHC(CO.sub.2 CH.sub.3).sub.2                                                                    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                            CH                                 L-2                                                                              0 CHC(CO.sub.2 CH.sub.3).sub.2                                                                    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHC(CO.sub.2 CH.sub.3).sub.2                                                                    H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 L-2                                                                              0 CHC(CO.sub.2 CH.sub.3).sub.2                                                                    H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                           N                                  L-2                                                                              0 CHC(CO.sub. 2 CH.sub.3).sub.2                                                                   H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  L-2                                                                              0 CHC(CO.sub.2 CH.sub.3).sub.2                                                                    H  H  -- Cl   OCH.sub.3                                                                           CH                                 __________________________________________________________________________

                                      TABLE IIIa                                  __________________________________________________________________________    General Structure IIIa                                                                                                      m.p.                            L  n W                R  R.sub.1                                                                          R.sub.2                                                                         X     Y      Z  (°C.)                    __________________________________________________________________________    L-2                                                                              0 CHCH.sub.2       H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              0 CHCH.sub.2       H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHCH.sub.2       H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHCH.sub.2       H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              0 CHCH.sub.2       H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              0 CHCH.sub.2       H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              0 CHCH.sub.2       H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                          H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                          H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                          H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                          H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                          H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                          H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                          H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                          H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                          H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                          H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                          H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                          H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                          H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                          H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                 H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                 H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                 H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                 H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                 H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                 H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                 H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                 H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                 H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                 H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                 H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                 H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                 H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                 H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHCHCN           H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              0 CHCHCN           H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHCHCN           H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHCHCN           H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              0 CHCHCN           H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              0 CHCHCN           H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              0 CHCHCN           H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHCHOCH.sub.3    H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              0 CHCHOCH.sub.3    H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHCHOCH.sub.3    H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHCHOCH.sub.3    H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              0 CHCHOCH.sub.3    H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              0 CHCHOCH.sub.3    H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              0 CHCHOCH.sub.3    H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                         H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                         H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                         H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                         H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                         H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                         H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                         H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHCHPh           H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              0 CHCHPh           H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHCHPh           H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHCHPh           H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              0 CHCHPh           H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              0 CHCHPh           H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              0 CHCHPh           H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              0 C(CH.sub.3)CHPh  H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              0 C(CH.sub.3)CHPh  H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              0 C(CH.sub.3)CHPh  H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0 C(CH.sub.3)CHPh  H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              0 C(CH.sub.3)CHPh  H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              0 C(CH.sub.3)CHPh  H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              0 C(CH.sub.3)CHPh  H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              0                                                                                ##STR150##      H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              0                                                                                ##STR151##      H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              0                                                                                ##STR152##      H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0                                                                                ##STR153##      H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              0                                                                                ##STR154##      H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              0                                                                                ##STR155##      H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              0                                                                                ##STR156##      H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              0                                                                                ##STR157##      H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              0                                                                                ##STR158##      H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              0                                                                                ##STR159##      H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0                                                                                ##STR160##      H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              0                                                                                ##STR161##      H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              0                                                                                ##STR162##      H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              0                                                                                ##STR163##      H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              0                                                                                ##STR164##      H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              0                                                                                ##STR165##      H  H  --                                                                              CH.sub.3                                                                            OCH.sub. 3                                                                           CH                                 L-2                                                                              0                                                                                ##STR166##      H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0                                                                                ##STR167##      H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              0                                                                                ##STR168##      H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              0                                                                                ##STR169##      H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              0                                                                                ##STR170##      H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              0 C(CN)CHCN        H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              0 C(CN)CHCN        H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              0 C(CN)CHCN        H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0 C(CN)CHCN        H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              0 C(CN)CHCN        H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              0 C(CN)CHCN        H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              0 C(CN)CHCN        H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                 H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                 H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                 H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                 H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                 H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                 H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                 H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                 H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                 H  H  --                                                                              CH.sub.3                                                                            OCH.sub. 3                                                                           CH                                 L-2                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                 H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                 H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                 H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                 H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                 H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              0                                                                                ##STR171##      CH.sub.3                                                                         H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0                                                                                ##STR172##      H  CH.sub.3                                                                         --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0 C(CH.sub.2)CH.sub.2 CH.sub.2 CH(NO.sub.2)CH.sub.3                                              H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHCHCH.sub.2 OSO.sub.2 Ph                                                                      H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHCHCH.sub. 2 OSO.sub.2 CH.sub.3                                                               H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHCHSCH.sub.3    H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0 CCH              H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              0 CCH              H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              0 CCH              H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0 CCH              H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              0 CCH              H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              0 CCH              H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              0 CCH              H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              0 CCPh             H  H  --                                                                              CH.sub.3                                                                            CH.sub. 3                                                                            CH                                 L-2                                                                              0 CCPh             H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              0 CCPh             H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0 CCPh             H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              0 CCPh             H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              0 CCPh             H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              0 CCPh             H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              0 CCCH.sub.3       H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              0 CCCH.sub.3       H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              0 CC CH.sub.3      H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0 CCCH.sub.3       H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              0 CCCH.sub.3       H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              0 CCCH.sub.3       H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              0 CCCH.sub.3       H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              0 CCCH.sub.2 OC(O)CH.sub.3                                                                       H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              0 CCCH.sub.2 OC(O)CH.sub.3                                                                       H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              0 CCCH.sub.2 OC(O)CH.sub.3                                                                       H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0 CCCH.sub.2 OC(O)CH.sub.3                                                                       H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              0 CCCH.sub.2 OC(O)CH.sub.3                                                                       H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              0 CCCH.sub.2 OC(O)CH.sub.3                                                                       H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              0 CCCH.sub.2 OC(O)CH.sub.3                                                                       H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              0 CCCH.sub.2 OH    H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              0 CCCH.sub.2 OH    H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              0 CCCH.sub.2 OH    H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0 CCCH.sub.2 OH    H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              0 CCCH.sub.2 OH    H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              0 CCCH.sub.2 OH    H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              0 CCCH.sub.2 OH    H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              0 CCCH.sub.2 Cl    H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              0 CCCH.sub.2 Cl    H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              0 CCCH.sub.2 Cl    H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0 CCCH.sub.2 Cl    H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              0 CCCH.sub.2 Cl    H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              0 CCCH.sub.2 Cl    H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              0 C CCH.sub.2 Cl   H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              0 CCCH.sub.2 Br    H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              0 CCCH.sub.2 Br    H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              0 CCCH.sub.2 Br    H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0 CCCH.sub.2 Br    H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              0 CCCH.sub.2 Br    H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              0 CCCH.sub.2 Br    H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              0 CCCH.sub.2 Br    H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              0 C CCH.sub.2 CN   H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              0 CCCH.sub.2 CN    H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              0 CCCH.sub.2 CN    H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0 CCCH.sub.2 CN    H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              0 CCCH.sub.2 CN    H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              0 CCCH.sub.2 CN    H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              0 CCCH.sub.2 CN    H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              0 CCCH.sub.2 OCH.sub.3                                                                           H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              0 C CCH.sub.2 OCH.sub.3                                                                          H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              0 CCCH.sub.2 OCH.sub.3                                                                           H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0 CCCH.sub.2 OCH.sub.3                                                                           H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              0 CCCH.sub.2 OCH.sub.3                                                                           H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              0 CCCH.sub.2 OCH.sub.3                                                                           H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              0 CCCH.sub.2 OCH.sub.3                                                                           H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              0 CCCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              0 CCCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                 H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0 CCCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              0 CCCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              0 CCCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              0 CCCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              0 CCCH.sub.2 SCH.sub.3                                                                           H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              0 CCCH.sub.2 SCH.sub.3                                                                           H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              0 CCCH.sub.2 SCH.sub.3                                                                           H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0 CCCH.sub.2 SCH.sub.3                                                                           H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              0 CCCH.sub.2 SCH.sub.3                                                                           H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              0 CCCH.sub.2 SCH.sub.3                                                                           H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              0 CCCH.sub.2 SCH.sub.3                                                                           H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              1 HCCH.sub.2       H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              1 HCCH.sub.2       H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              1 HCCH.sub.2       H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              1 HCCH.sub.2       H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              1 HCCH.sub.2       H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              1 HCCH.sub.2       H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              1 HCCH.sub.2       H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              1 HCC(CH.sub.3).sub.2                                                                            H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              1 HCC(CH.sub.3).sub.2                                                                            H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              1 HCC(CH.sub.3).sub.2                                                                            H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              1 HCC(CH.sub.3).sub.2                                                                            H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              1 HCC(CH.sub.3).sub.2                                                                            H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              1 HCC(CH.sub.3).sub.2                                                                            H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              1 HCC(CH.sub.3).sub.2                                                                            H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              1 HCC(CH.sub.3)CH.sub.2 CHC(CH.sub.3).sub.2                                                      H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              1 HCC(CH.sub.3)CH.sub.2 CHC(CH.sub.3).sub.2                                                      H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              1 HCC(CH.sub.3)CH.sub.2 CHC(CH.sub.3).sub.2                                                      H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              1 HCC(CH.sub.3)CH.sub.2 CHC(CH.sub.3).sub.2                                                      H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              1 HCC(CH.sub. 3)CH.sub.2 CHC(CH.sub.3).sub.2                                                     H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              1 HCC(CH.sub.3)CH.sub.2 CHC(CH.sub.3).sub.2                                                      H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              1 HCC(CH.sub.3)CH.sub.2 CHC(CH.sub.3).sub.2                                                      H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              1 HCCHPh           H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              1 HCCHPh           H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              1 HCCHPh           H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              1 HCCHPh           H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              1 HCCHPh           H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              1 HCCHPh           H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              1 HCCHPh           H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              1 HCCHCH.sub.3     H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              1 HCCHCH.sub.3     H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              1 HCCHCH.sub.3     H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              1 HC CHCH.sub.3    H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              1 HCCHCH.sub.3     H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              1 HCCHCH.sub.3     H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              1 HCCHCH.sub.3     H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              1 CCH              H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              1 CCH              H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              1 CCH              H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              1 CCH              H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              1 CCH              H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              1 CCH              H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              1 CCH              H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              1 CCCH.sub.3       H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              1 C CCH.sub.3      H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              1 CCCH.sub.3       H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              1 CCCH.sub.3       H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              1 CCCH.sub.3       H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              1 CCCH.sub.3       H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              1 CCCH.sub.3       H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              1 CCCH.sub.2 Br    H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              1 C CCH.sub.2 Br   H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              1 CCCH.sub.2 Br    H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              1 CCCH.sub.2 Br    H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              1 CCCH.sub.2 Br    H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              1 CCCH.sub.2 Br    H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              1 CCCH.sub.2 Br    H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              1 CCPh             H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              1 CCPh             H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              1 CCPh             H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              1 CCPh             H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              1 CCPh             H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              1 CCPh             H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              1 CCPh             H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              1 CHCH.sub.2       CH.sub.3                                                                         H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              1 CHCH.sub.2       CH.sub.3                                                                         H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              1 CHCH.sub.2       CH.sub.3                                                                         H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              1 CHCH.sub.2       CH.sub.3                                                                         H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              1 CHCH.sub.2       CH.sub.3                                                                         H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              1 CHCH.sub.2       CH.sub.3                                                                         H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              1 CHCH.sub.2       CH.sub.3                                                                         H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              1 CCH              CH.sub.3                                                                         H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              1 CCH              CH.sub.3                                                                         H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              1 CCH              CH.sub.3                                                                         H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              1 CCH              CH.sub.3                                                                         H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              1 CCH              CH.sub.3                                                                         H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              1 CCH              CH.sub.3                                                                         H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              1 CCH              CH.sub.3                                                                         H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              1 CHCH.sub.2       H  CH.sub.3                                                                         --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              1 CHCH.sub.2       H  CH.sub.3                                                                         --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              1 CHCH.sub.2       H  CH.sub. 3                                                                        --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              1 CHCH.sub.2       H  CH.sub.3                                                                         --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             N                                  L-2                                                                              1 CHCH.sub.2       H  CH.sub.3                                                                         --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              1 CHCH.sub.2       H  CH.sub.3                                                                         --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              1 CHCH.sub.2       H  CH.sub.3                                                                         --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              1 CCH              H  CH.sub.3                                                                         --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              1 CCH              H  CH.sub.3                                                                         --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              1 CCH              H  CH.sub.3                                                                         --                                                                              OCH.sub.3                                                                           CH.sub.3                                                                             CH                                 L-2                                                                              0 CHC(CN).sub.2    H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              0 CHC(CN).sub.2    H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHC(CN).sub.2    H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHC(CN).sub.2    H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              0 CHC(CN).sub.2    H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              0 CHC(CN).sub.2    H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.2 CH.sub.3                                                              H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.2 CH.sub.3                                                              H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.2 CH.sub.3                                                              H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.2 CH.sub.3                                                              H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.2 CH.sub.3                                                              H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.2 CH.sub.3                                                              H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHC(CO.sub.2 CH.sub.2 CH.sub.3).sub.2                                                          H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              0 CHC(CO.sub.2 CH.sub.2 CH.sub.3).sub.2                                                          H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHC(CO.sub.2 CH.sub.2 CH.sub.3).sub.2                                                          H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHC(CO.sub.2 CH.sub.2 CH.sub.3).sub.2                                                          H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              0 CHC(CO.sub.2 CH.sub.2 CH.sub.3).sub.2                                                          H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              0 CHC(CO.sub.2 CH.sub.2 CH.sub.3).sub.2                                                          H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.3                                                                       H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.3                                                                       H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.3                                                                       H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.3                                                                       H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.3                                                                       H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.3                                                                       H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHC(CO.sub.2 CH.sub.3).sub.2                                                                   H  H  --                                                                              CH.sub.3                                                                            CH.sub.3                                                                             CH                                 L-2                                                                              0 CHC(CO.sub.2 CH.sub.3).sub.2                                                                   H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHC(CO.sub.2 CH.sub.3).sub.2                                                                   H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHC(CO.sub.2 CH.sub. 3).sub.2                                                                  H  H  --                                                                              CH.sub.3                                                                            OCH.sub.3                                                                            N                                  L-2                                                                              0 CHC(CO.sub.2 CH.sub.3).sub.2                                                                   H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                            N                                  L-2                                                                              0 CHC(CO.sub.2 CH.sub.3).sub.2                                                                   H  H  --                                                                              Cl    OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHCH.sub.2       H  H  --                                                                              OCH.sub.3                                                                            ##STR173##                                                                          N                                  L-2                                                                              0 CHCH.sub.2       H  H  --                                                                              OCH.sub.3                                                                           NHCH.sub.3                                                                           N                                  L-2                                                                              0 CHCH.sub.2       H  H  --                                                                              OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                           N                                  L-2                                                                              0 CHCH.sub.2       H  H  --                                                                              OCF.sub.2 H                                                                         OCH.sub.3                                                                            CH                                 L-2                                                                              0 CHCH.sub.2       H  H  --                                                                              OCH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                             CH                                 L-2                                                                              0 CHCH.sub.2       H  H  --                                                                              OCH.sub.3                                                                           OCH.sub.2 CF.sub.3                                                                   N                                  __________________________________________________________________________

                                      TABLE IIIb                                  __________________________________________________________________________    General Structure IIIb                                                                                                        m.p.                          L  n W                 R  R.sub.1                                                                          R.sub.2                                                                          X     Y      Z  (°C.)                  __________________________________________________________________________    L-2                                                                              0 CHCH.sub.2        H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              0 CHCH.sub.2        H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              0 CHCH.sub.2        H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0 CHCH.sub.2        H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              0 CHCH.sub.2        H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              0 CHCH.sub.2        H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              0 CHCH.sub.2        H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0 C(CH.sub.3 )CHCH.sub.3                                                                          H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              0 CHCHCN            H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              0 CHCHCN            H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              0 CHCHCN            H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0 CHCHCN            H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              0 CHCHCN            H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              0 CHCHCN            H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              0 CHCHCN            H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              0 CHCHOCH.sub.3     H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              0 CHCHOCH.sub.3     H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              0 CHCHOCH.sub.3     H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0 CHCHOCH.sub.3     H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              0 CHCHOCH.sub.3     H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              0 CHCHOCH.sub.3     H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              0 CHCHOCH.sub.3     H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              0 CHCHPh            H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              0 CHCHPh            H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              0 CHCHPh            H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0 CHCHPh            H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              0 CHCHPh            H  H  -- CH.sub. 3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              0 CHCHPh            H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              0 CHCHPh            H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              0 C(CH.sub.3)CHPh   H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              0 C(CH.sub.3)CHPh   H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              0 C(CH.sub.3)CHPh   H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0 C(CH.sub.3)CHPh   H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              0 C(CH.sub.3)CHPh   H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              0 C(CH.sub.3)CHPh   H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              0 C(CH.sub.3)CHPh   H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              0                                                                                ##STR174##       H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              0                                                                                ##STR175##       H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              0                                                                                ##STR176##       H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0                                                                                ##STR177##       H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              0                                                                                ##STR178##       H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              0                                                                                ##STR179##       H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              0                                                                                ##STR180##       H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              0                                                                                ##STR181##       H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              0                                                                                ##STR182##       H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              0                                                                                ##STR183##       H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0                                                                                ##STR184##       H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              0                                                                                ##STR185##       H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              0                                                                                ##STR186##       H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              0                                                                                ##STR187##       H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              0                                                                                ##STR188##       H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              0                                                                                ##STR189##       H  H  -- CH.sub.3                                                                            OCH.sub. 3                                                                           CH                               L-2                                                                              0                                                                                ##STR190##       H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0                                                                                ##STR191##       H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              0                                                                                ##STR192##       H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              0                                                                                ##STR193##       H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              0                                                                                ##STR194##       H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              0 C(CN)CHCN         H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              0 C(CN)CHCN         H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              0 C(CN)CHCN         H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0 C(CN)CHCN         H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              0 C(CN)CHCN         H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              0 C(CN)CHCN         H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              0 C(CN)CHCN         H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              0                                                                                ##STR195##       CH.sub.3                                                                         H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0                                                                                ##STR196##       H  CH.sub.3                                                                         -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0 C(CH.sub.2)CH.sub.2 CH.sub.2 CH(NO.sub.2)CH.sub.3                                               H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0 CHCHCH.sub.2 OSO.sub.2 Ph                                                                       H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0 CHCHCH.sub.2 OSO.sub.2 CH.sub.3                                                                 H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0 CHCHSCH.sub.3     H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0 CCH               H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              0 CCH               H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              0 CCH               H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0 CCH               H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              0 CCH               H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              0 CCH               H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              0 CCH               H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              0 C CPh             H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              0 CCPh              H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              0 CCPh              H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0 CCPh              H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              0 CCPh              H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              0 CCPh              H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              0 CCPh              H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              0 CCCH.sub.3        H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              0 CCCH.sub.3        H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              0 C CCH.sub.3       H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0 CCCH.sub.3        H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              0 CCCH.sub.3        H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              0 CCCH.sub.3        H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              0 CCCH.sub.3        H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              0 CCCH.sub.2 OC(O)CH.sub.3                                                                        H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              0 CCCH.sub.2 OC(O)CH.sub.3                                                                        H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              0 CCCH.sub.2 OC(O)CH.sub.3                                                                        H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0 C CCH.sub.2 OC(O)CH.sub.3                                                                       H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              0 CCCH.sub.2 OC(O)CH.sub.3                                                                        H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              0 CCCH.sub.2 OC(O)CH.sub.3                                                                        H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              0 CCCH.sub.2 OC(O)CH.sub.3                                                                        H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              0 CCCH.sub.2 OH     H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              0 CCCH.sub.2 OH     H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              0 CCCH.sub.2 OH     H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0 CCCH.sub.2 OH     H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              0 CCCH.sub.2 OH     H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              0 CCCH.sub.2 OH     H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              0 CCCH.sub.2 OH     H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              0 CCCH.sub.2 Cl     H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              0 CCCH.sub.2 Cl     H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              0 CCCH.sub.2 Cl     H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0 CCCH.sub.2 Cl     H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              0 CCCH.sub.2 Cl     H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              0 CCCH.sub.2 Cl     H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              0 CCCH.sub.2 Cl     H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              0 CCCH.sub.2 Br     H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              0 CCCH.sub.2 Br     H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              0 CCCH.sub.2 Br     H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0 CCCH.sub.2 Br     H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              0 CCCH.sub.2 Br     H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              0 CCCH.sub.2 Br     H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              0 CCCH.sub.2 Br     H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              0 C CCH.sub.2 CN    H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              0 CCCH.sub.2 CN     H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              0 CCCH.sub.2 CN     H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0 CCCH.sub.2 CN     H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              0 CCCH.sub.2 CN     H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              0 CCCH.sub.2 CN     H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              0 CCCH.sub.2 CN     H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              0 CCCH.sub.2 OCH.sub.3                                                                            H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              0 C CCH.sub.2 OCH.sub.3                                                                           H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              0 CCCH.sub.2 OCH.sub.3                                                                            H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0 CCCH.sub.2 OCH.sub.3                                                                            H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              0 CCCH.sub.2 OCH.sub.3                                                                            H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              0 CCCH.sub.2 OCH.sub.3                                                                            H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              0 CCCH.sub.2 OCH.sub.3                                                                            H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              0 CCCH.sub.2 OSO.sub.2 CH.sub.3                                                                   H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              0 CCCH.sub.2 OSO.sub.2 CH.sub.3                                                                   H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              0 CCCH.sub.2 OSO.sub.2 CH.sub.3                                                                   H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0 CCCH.sub.2 OSO.sub.2 CH.sub.3                                                                   H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              0 CCCH.sub.2 OSO.sub.2 CH.sub.3                                                                   H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              0 CCCH.sub.2 OSO.sub.2 CH.sub.3                                                                   H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              0 CCCH.sub.2 OSO.sub.2 CH.sub.3                                                                   H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              0 CCCH.sub.2 SCH.sub.3                                                                            H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              0 CCCH.sub.2 SCH.sub.3                                                                            H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              0 C CCH.sub.2 SCH.sub.3                                                                           H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0 CCCH.sub.2 SCH.sub.3                                                                            H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              0 CCCH.sub.2 SCH.sub.3                                                                            H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              0 CCCH.sub.2 SCH.sub.3                                                                            H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              0 CCCH.sub.2 SCH.sub.3                                                                            H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              1 HCCH.sub.2        H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              1 HCCH.sub.2        H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              1 HCCH.sub.2        H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              1 HCCH.sub.2        H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              1 HCCH.sub.2        H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              1 HCCH.sub.2        H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              1 HCCH.sub.2        H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              1 HCC(CH.sub.3)CH.sub.2 CH.sub.2 CHC(CH.sub.3).sub.2                                              H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              1 HCCHPh            H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              1 HCCHPh            H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              1 HCCHPh            H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              1 HCCHPh            H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              1 HCCHPh            H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              1 HCCHPh            H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              1 HCCHPh            H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              1 HCCHCH.sub.3      H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              1 HCCHCH.sub.3      H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              1 HCCHCH.sub.3      H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              1 HCCHCH.sub.3      H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              1 HCCHCH.sub.3      H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              1 HCCHCH.sub.3      H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              1 HCCHCH.sub.3      H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              1 CCH               H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              1 CCH               H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              1 CCH               H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              1 CCH               H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              1 CCH               H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              1 CCH               H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              1 CCH               H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              1 CCCH.sub.3        H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              1 CCCH.sub.3        H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              1 CCCH.sub.3        H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              1 CCCH.sub.3        H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              1 CCCH.sub.3        H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              1 CCCH.sub.3        H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              1 CCCH.sub.3        H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              1 C CCH.sub.2 Br    H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              1 CCCH.sub.2 Br     H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              1 CCCH.sub.2 Br     H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              1 CCCH.sub.2 Br     H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              1 CCCH.sub.2 Br     H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              1 CCCH.sub.2 Br     H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              1 CCCH.sub.2 Br     H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              1 CCPh              H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              1 CCPh              H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              1 CCPh              H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              1 CCPh              H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              1 CCPh              H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              1 CCPh              H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              1 CCPh              H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              1 CCH               H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              1 CCH               H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              1 CCH               H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              1 CCH               H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              1 CCH               H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              1 CCH               H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              1 CCH               H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         -- CH.sub.3                                                                            CH.sub.3                                                                             N                                L-2                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              1 CCH               H  CH.sub.3                                                                         -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              1 CCH               H  CH.sub.3                                                                         -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              1 CCH               H  CH.sub.3                                                                         -- OCH.sub.3                                                                           CH.sub.3                                                                             CH                               L-3                                                                              0 CHCH.sub.2        H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              0 CHCH.sub.2        H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              0 CHCH.sub.2        H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              0 CHCH.sub.2        H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              0 CHCH.sub.2        H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              0 CHCH.sub.2        H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              0 CHCH.sub.2        H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              0 C(CH.sub.3)CHCH.sub.3                                                                           H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              0 CHCHCH.sub.2 CH.sub.3                                                                           H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              0 C(CH.sub.3)CHCH.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              0 CH CHCH.sub.2 CH.sub.2 CH.sub.3                                                                 H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-4                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              0 CHCHCH.sub.2 CH.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              0 CHCHCN            H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              0 CHCHCN            H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              0 CHCHCN            H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              0 CHCHCN            H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              0 CHCHCN            H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              0 CHCHCN            H  H  CH.sub. 3                                                                        OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              0 CHCHCN            H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              0 CHCHOCH.sub.3     H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              0 CHCHOCH.sub.3     H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              0 CHCHOCH.sub.3     H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              0 CHCHOCH.sub.3     H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              0 CHCHOCH.sub.3     H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              0 CHCHOCH.sub.3     H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              0 CHCHOCH.sub.3     H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              0 C(CH.sub.3)CHOCH.sub.3                                                                          H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              0 CHCHPh            H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              0 CHCHPh            H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              0 CHCHPh            H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              0 CHCHPh            H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              0 CHCHPh            H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              0 CHCHPh            H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              0 CHCHPh            H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              0 C(CH.sub.3)CHPh   H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              0 C(CH.sub.3)CHPh   H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              0 C(CH.sub.3)CHPh   H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              0 C(CH.sub.3)CHPh   H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              0 C(CH.sub.3) CHPh  H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              0 C(CH.sub.3)CHPh   H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              0 C(CH.sub.3)CHPh   H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              0                                                                                ##STR197##       H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              0                                                                                ##STR198##       H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              0                                                                                ##STR199##       H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              0                                                                                ##STR200##       H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              0                                                                                ##STR201##       H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              0                                                                                ##STR202##       H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              0                                                                                ##STR203##       H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              0                                                                                ##STR204##       H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              0                                                                                ##STR205##       H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              0                                                                                ##STR206##       H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              0                                                                                ##STR207##       H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              0                                                                                ##STR208##       H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              0                                                                                ##STR209##       H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              0                                                                                ##STR210##       H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              0                                                                                ##STR211##       H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              0                                                                                ##STR212##       H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              0                                                                                ##STR213##       H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              0                                                                                ##STR214##       H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              0                                                                                ##STR215##       H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              0                                                                                ##STR216##       H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              0                                                                                ##STR217##       H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              0 C(CN)CHCN         H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              0 C(CN)CHCN         H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              0 C(CN)CHCN         H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              0 C(CN)CHCN         H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              0 C(CN)CHCN         H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              0 C(CN)CHCN         H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              0 C(CN)CHCN         H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              0 CHCHSO.sub.2 N(CH.sub.3).sub.2                                                                  H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              0 C(CH.sub.3)CHCO.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              0                                                                                ##STR218##       CH.sub.3                                                                         H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              0                                                                                ##STR219##       H  CH.sub.3                                                                         CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              0                                                                                ##STR220##       H  CH.sub.3                                                                         CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              0 C(CH.sub.2)CH.sub.2 CH.sub.2 CH(NO.sub.2)CH.sub.3                                               H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              0 CHCHCH.sub.2 OSO.sub.2 Ph                                                                       H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              0 CHCHCH.sub.2 OSO.sub.2 CH.sub.3                                                                 H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              0 CHCHSCH.sub.3     H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              0 CCH               H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              0 CCH               H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              0 C CH              H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              0 CCH               H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              0 CCH               H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              0 CCH               H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              0 CCH               H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              0 CCPh              H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              0 CCPh              H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              0 CCPh              H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              0 CCPh              H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              0 C CPh             H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              0 CCPh              H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              0 CCPh              H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              0 CCCH.sub.3        H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              0 CCCH.sub.3        H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              0 CCCH.sub.3        H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              0 CCCH.sub.3        H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              0 CCCH.sub.3        H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              0 CCCH.sub.3        H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub. 3                                                                           N                                L-3                                                                              0 CCCH.sub.3        H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              0 CCCH.sub.2 OC(O)CH.sub.3                                                                        H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              0 CCCH.sub.2 OC(O)CH.sub.3                                                                        H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              0 CCCH.sub.2 OC(O)CH.sub.3                                                                        H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              0 CCCH.sub.2 OC(O)CH.sub.3                                                                        H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              0 CCCH.sub.2 OC(O)CH.sub.3                                                                        H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              0 CCCH.sub.2 OC(O)CH.sub.3                                                                        H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              0 CCCH.sub.2 OC(O)CH.sub.3                                                                        H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              0 CCCH.sub.2 OH     H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              0 CCCH.sub.2 OH     H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              0 CCCH.sub.2 OH     H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              0 CCCH.sub.2 OH     H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              0 CCCH.sub.2 OH     H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              0 CCCH.sub.2 OH     H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              0 CCCH.sub.2 OH     H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              0 CCCH.sub.2 Cl     H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              0 C CCH.sub.2 Cl    H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              0 CCCH.sub.2 Cl     H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              0 CCCH.sub.2 Cl     H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              0 CCCH.sub.2 Cl     H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              0 CCCH.sub.2 Cl     H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              0 CCCH.sub.2 Cl     H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              0 CCCH.sub.2 Br     H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              0 CCCH.sub.2 Br     H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              0 CCCH.sub.2 Br     H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              0 CCCH.sub.2 Br     H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              0 CCCH.sub.2 Br     H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              0 CCCH.sub.2 Br     H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              0 CCCH.sub.2 Br     H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              0 CCCH.sub.2 CN     H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              0 CCCH.sub.2 CN     H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              0 CCCH.sub.2 CN     H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              0 CCCH.sub.2 CN     H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              0 CCCH.sub.2 CN     H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              0 CCCH.sub.2 CN     H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              0 CCCH.sub.2 CN     H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              0 CCCH.sub.2 OCH.sub.3                                                                            H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              0 CCCH.sub.2 OCH.sub.3                                                                            H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              0 CCCH.sub.2 OCH.sub.3                                                                            H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              0 CCCH.sub.2 OCH.sub.3                                                                            H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              0 CCCH.sub.2 OCH.sub.3                                                                            H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              0 CCCH.sub.2 OCH.sub.3                                                                            H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              0 CCCH.sub.2 OCH.sub.3                                                                            H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              0 CCCH.sub.2 OSO.sub.2 CH.sub.3                                                                   H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              0 CCCH.sub.2 OSO.sub.2 CH.sub.3                                                                   H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              0 CCCH.sub.2 OSO.sub.2 CH.sub.3                                                                   H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              0 CCCH.sub.2 OSO.sub.2 CH.sub.3                                                                   H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              0 CCCH.sub.2 OSO.sub.2 CH.sub.3                                                                   H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              0 C CCH.sub.2 OSO.sub.2 CH.sub.3                                                                  H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              0 CCCH.sub.2 OSO.sub.2 CH.sub.3                                                                   H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              0 CCCH.sub.2 SCH.sub.3                                                                            H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              0 CCCH.sub.2 SCH.sub.3                                                                            H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              0 CCCH.sub.2 SCH.sub.3                                                                            H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              0 CCCH.sub.2 SCH.sub.3                                                                            H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              0 CCCH.sub.2 SCH.sub.3                                                                            H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              0 CCCH.sub.2 SCH.sub.3                                                                            H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              0 CCCH.sub.2 SCH.sub.3                                                                            H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              1 HCCH.sub.2        H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              1 HCCH.sub.2        H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              1 HCCH.sub.2        H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              1 HCCH.sub.2        H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              1 HCCH.sub.2        H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              1 HCCH.sub.2        H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              1 HCCH.sub.2        H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              1 HCC(CH.sub.3).sub.2                                                                             H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              1 HCC(CH.sub.3)CH.sub.2 CHC(CH.sub.3).sub.2                                                       H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              1 HCC(CH.sub.3)CH.sub.2 CHC(CH.sub.3).sub.2                                                       H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              1 HCC(CH.sub.3)CH.sub.2 CHC(CH.sub.3).sub.2                                                       H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              1 HCC(CH.sub.3)CH.sub.2 CHC(CH.sub.3).sub.2                                                       H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              1 HCC(CH.sub.3)CH.sub.2 CHC(CH.sub.3).sub.2                                                       H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              1 HCC(CH.sub.3)CH.sub.2 CHC(CH.sub.3).sub.2                                                       H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              1 HCC(CH.sub.3)CH.sub.2 CHC(CH.sub.3).sub.2                                                       H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              1 HCCHPh            H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              1 HCCHPh            H  H  CH.sub.3                                                                         CH.sub. 3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              1 HCCHPh            H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              1 HCCHPh            H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              1 HCCHPh            H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              1 HCCHPh            H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              1 HCCHPh            H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              1 HCCHCH.sub.3      H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              1 HCCHCH.sub.3      H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              1 HCCHCH.sub.3      H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              1 HCCHCH.sub.3      H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              1 HCCHCH.sub.3      H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              1 HCCHCH.sub.3      H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              1 HCCHCH.sub.3      H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              1 CCH               H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              1 C CH              H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              1 CCH               H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              1 CCH               H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              1 CCH               H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              1 CCH               H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              1 CCH               H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              1 CCCH.sub.3        H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              1 CCCH.sub.3        H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              1 CCCH.sub.3        H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              1 C CCH.sub.3       H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              1 CCCH.sub.3        H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              1 CCCH.sub.3        H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              1 CCCH.sub.3        H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              1 CCCH.sub.2 Br     H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              1 CCCH.sub.2 Br     H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              1 CCCH.sub.2 Br     H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              1 CCCH.sub.2 Br     H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              1 CCCH.sub.2 Br     H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              1 CCCH.sub.2 Br     H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              1 CCCH.sub.2 Br     H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              1 CCPh              H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              1 CCPh              H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              1 CCPh              H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              1 CCPh              H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              1 CCPh              H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              1 CCPh              H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              1 C CPh             H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              1 CHCH.sub.2        CH.sub.3                                                                         H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              1 CCH               H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              1 CCH               H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            OH                               L-3                                                                              1 CCH               H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              1 CCH               H  H  CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              1 CCH               H  H  CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              1 CCH               H  H  CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              1 CCH               H  H  CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-3                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-3                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         CH.sub.3                                                                         CH.sub.3                                                                            CH.sub.3                                                                             N                                L-3                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         CH.sub.3                                                                         CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-3                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              1 CHCH.sub.2        H  CH.sub.3                                                                         CH.sub.3                                                                         Cl    OCH.sub.3                                                                            CH                               L-3                                                                              1 CCH               H  CH.sub.3                                                                         CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-3                                                                              1 CCH               H  CH.sub.3                                                                         CH.sub.3                                                                         OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-3                                                                              1 CCH               H  CH.sub.3                                                                         CH.sub.3                                                                         OCH.sub.3                                                                           CH.sub.3                                                                             CH                               L-2                                                                              0 CHC(CN).sub.2     H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              0 CHC(CN).sub.2     H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              0 CHC(CN).sub.2     H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0 CHC(CN).sub.2     H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              0 CHC(CN).sub.2     H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              0 CHC(CN).sub.2     H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.2 CH.sub.3                                                               H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.2 CH.sub.3                                                               H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.2 CH.sub.3                                                               H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.2 CH.sub.3                                                               H  H  -- CH.sub.3                                                                            OCH.sub. 3                                                                           N                                L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.2 CH.sub.3                                                               H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.2 CH.sub.3                                                               H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              0 CHC(CO.sub.2 CH.sub.2 CH.sub.3).sub.2                                                           H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              0 CHC(CO.sub.2 CH.sub.2 CH.sub.3).sub.2                                                           H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              0 CHC(CO.sub.2 CH.sub.2 CH.sub.3).sub.2                                                           H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0 CHC(CO.sub.2 CH.sub.2 CH.sub.3).sub.2                                                           H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              0 CHC(CO.sub.2 CH.sub.2 CH.sub.3).sub.2                                                           H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              0 CHC(CO.sub.2 CH.sub.2 CH.sub.3).sub.2                                                           H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.3                                                                        H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.3                                                                        H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.3                                                                        H  H  -- OCH.sub. 3                                                                          OCH.sub.3                                                                            CH                               L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.3                                                                        H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.3                                                                        H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              0 CHC(CN)CO.sub.2 CH.sub.3                                                                        H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              0 CHC(CO.sub.2 CH.sub.3).sub.2                                                                    H  H  -- CH.sub.3                                                                            CH.sub.3                                                                             CH                               L-2                                                                              0 CHC(CO.sub.2 CH.sub.3).sub.2                                                                    H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            CH                               L-2                                                                              0 CHC(CO.sub.2 CH.sub.3).sub.2                                                                    H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            CH                               L-2                                                                              0 CHC(CO.sub.2 CH.sub.3).sub.2                                                                    H  H  -- CH.sub.3                                                                            OCH.sub.3                                                                            N                                L-2                                                                              0 CHC(CO.sub.2 CH.sub.3).sub.2                                                                    H  H  -- OCH.sub.3                                                                           OCH.sub.3                                                                            N                                L-2                                                                              0 CHC(CO.sub.2 CH.sub.3).sub.2                                                                    H  H  -- Cl    OCH.sub.3                                                                            CH                               L-2                                                                              0 CHCH.sub.2        H  H  -- OCH.sub.2 CH.sub.3                                                                  CH.sub.3                                                                             CH                               L-2                                                                              0 CHCH.sub.2        H  H  -- OCH.sub.2 CH.sub.3                                                                  NHCH.sub.3                                                                           N                                L-2                                                                              0 CHCH.sub.2        H  H  -- OCH.sub. 3                                                                          N(CH.sub.3).sub.2                                                                    N                                L-2                                                                              0 CHCH.sub.2        H  H  -- OCH.sub.3                                                                           CH(CH.sub.3).sub.2                                                                   N                                L-2                                                                              0 CHCH.sub.2        H  H  -- OCH.sub.3                                                                           CH.sub.2 OCH.sub.3                                                                   CH                               L-2                                                                              0 CHCH.sub.2        H  H  -- CH.sub.3                                                                            OCH.sub.2 CH.sub.2 F                                                                 N                                L-2                                                                              0 CHCH.sub.2        H  H  -- OCH.sub.3                                                                           CH(OCH.sub.3).sub.2                                                                  CH                               L-2                                                                              0 CHCH.sub.2        H  H  -- Br    OCH.sub.3                                                                            CH                               L-2                                                                              0 CHCH.sub.2        H  H  -- OCH.sub.3                                                                           OCH.sub.2 CF.sub.3                                                                   N                                L-2                                                                              0 CHCH.sub.2        H  H  -- OCH.sub.3                                                                           H      CH                               __________________________________________________________________________

                                      TABLE IV                                    __________________________________________________________________________    General Structure IV                                                          A  W      R R.sub.1                                                                         X.sub.1                                                                            Y.sub.1                                                                          Y.sub.2                                                                          X.sub.2                                                                           Y.sub.3                                                                            X.sub.3                                                                          m.p. (°C.)                        __________________________________________________________________________    A-2                                                                              C.tbd.C--CH.sub.2 F                                                                  H H CH.sub.3                                                                           O  -- --  --   --                                          A-2                                                                              C.tbd.C--CH.sub.2 F                                                                  H H CH.sub.3                                                                           CH.sub.2                                                                         -- --  --   --                                          A-2                                                                              C.tbd.C--CH.sub.2 F                                                                  H H OCH.sub.3                                                                          O  -- --  --   --                                          A-2                                                                              C.tbd.C--CH.sub.2 F                                                                  H H OCF.sub.2 H                                                                        O  -- --  --   --                                          A-3                                                                              C.tbd.C--CH.sub.2 F                                                                  H H CH.sub.3                                                                           -- -- --  --   --                                          A-3                                                                              C.tbd.C--CH.sub.2 F                                                                  H H OCH.sub.3                                                                          -- -- --  --   --                                          A-3                                                                              C.tbd.C--CH.sub.2 F                                                                  H H OCF.sub.2 H                                                                        -- -- --  --   --                                          A-4                                                                              C.tbd.C--CH.sub.2 F                                                                  H H CH.sub.3                                                                           -- H  --  --   --                                          A-4                                                                              C.tbd.C--CH.sub.2 F                                                                  H H OCH.sub.3                                                                          -- H  --  --   --                                          A-4                                                                              C.tbd.C--CH.sub.2 F                                                                  H H CH.sub.3                                                                           -- CH.sub.3                                                                         --  --   --                                          A-4                                                                              C.tbd.C--CH.sub.2 F                                                                  H H OCH.sub.3                                                                          -- CH.sub.3                                                                         --  --   --                                          A-5                                                                              C.tbd.C--CH.sub.2 F                                                                  H H --   -- -- CH.sub.3                                                                          CH.sub.3                                                                           --                                          A-5                                                                              C.tbd.C--CH.sub.2 F                                                                  H H --   -- -- OCH.sub.3                                                                         CH.sub.3                                                                           --                                          A-5                                                                              C.tbd.C--CH.sub.2 F                                                                  H H --   -- -- CH.sub.3                                                                          CH.sub.2 CF.sub.3                                                                  --                                          A-6                                                                              C.tbd.C--CH.sub.2 F                                                                  H H --   -- -- --  --   CH.sub.3                                    __________________________________________________________________________

                                      TABLE V                                     __________________________________________________________________________    General Structure V                                                           L  W       A  n X.sub.1                                                                           Y.sub.1                                                                          Y.sub.2                                                                          X.sub.2                                                                           Y.sub.3                                                                          X.sub.3                                                                          X.sub.4                                                                           Y.sub.4                                                                             m.p. (°C.)               __________________________________________________________________________    L-2                                                                               ##STR221##                                                                           A-2                                                                              O CH.sub.3                                                                          O  -- --  -- -- --  --                                    L-2                                                                               ##STR222##                                                                           A-2                                                                              O OCH.sub.3                                                                         O  -- --  -- -- --  --                                    L-2                                                                               ##STR223##                                                                           A-2                                                                              O CH.sub.3                                                                          CH -- --  -- -- --  --                                    L-2                                                                               ##STR224##                                                                           A-3                                                                              O OCH.sub.3                                                                         -- -- --  -- -- --  --                                    L-2                                                                               ##STR225##                                                                           A-4                                                                              O OCH.sub.3                                                                         -- CH.sub.3                                                                         --  -- -- --  --                                    L-2                                                                               ##STR226##                                                                           A-5                                                                              O --  -- -- OCH.sub.3                                                                         CH.sub.3                                                                         -- --  --                                    L-2                                                                               ##STR227##                                                                           A-6                                                                              O --  -- -- --  -- CH.sub.3                                                                         --  --                                    L-3                                                                               ##STR228##                                                                           A-2                                                                              O CH.sub.3                                                                          O  -- --  -- -- --  --                                    L-3                                                                               ##STR229##                                                                           A-3                                                                              O OCH.sub.3                                                                         -- -- --  -- -- --  --                                    L-3                                                                               ##STR230##                                                                           A-4                                                                              O OCH.sub.3                                                                         -- CH.sub.3                                                                         --  -- -- --  --                                    L-3                                                                               ##STR231##                                                                           A-5                                                                              O --  -- -- OCH.sub.3                                                                         CH.sub.3                                                                         -- --  --                                    L-3                                                                               ##STR232##                                                                           A-6                                                                              O --  -- -- --  -- CH.sub.3                                                                         --  --                                    L-4                                                                               ##STR233##                                                                           A-2                                                                              O CH.sub.3                                                                          O  -- --  -- -- --  --                                    L-4                                                                               ##STR234##                                                                           A-3                                                                              O OCH.sub.3                                                                         -- -- --  -- -- --  --                                    L-4                                                                               ##STR235##                                                                           A-4                                                                              O OCH.sub.3                                                                         -- CH.sub.3                                                                         --  -- -- --  --                                    L-4                                                                               ##STR236##                                                                           A-5                                                                              O --  -- -- OCH.sub.3                                                                         CH.sub.3                                                                         -- --  --                                    L-4                                                                               ##STR237##                                                                           A-6                                                                              O --  -- -- --  -- CH.sub.3                                                                         --  --                                    L-5                                                                               ##STR238##                                                                           A-2                                                                              O CH.sub.3                                                                          O  -- --  -- -- --  --                                    L-5                                                                               ##STR239##                                                                           A-3                                                                              O OCH.sub.3                                                                         -- -- --  -- -- --  --                                    L-5                                                                               ##STR240##                                                                           A-4                                                                              O OCH.sub.3                                                                         -- CH.sub.3                                                                         --  -- -- --  --                                    L-5                                                                               ##STR241##                                                                           A-5                                                                              O --  -- -- OCH.sub.3                                                                         CH.sub.3                                                                         -- --  --                                    L-5                                                                               ##STR242##                                                                           A-6                                                                              O --  -- -- --  -- CH.sub.3                                                                         --  --                                    L-6                                                                               ##STR243##                                                                           A-2                                                                              O CH.sub.3                                                                          O  -- --  -- -- --  --                                    L-6                                                                               ##STR244##                                                                           A-3                                                                              O OCH.sub.3                                                                         -- -- --  -- -- --  --                                    L-6                                                                               ##STR245##                                                                           A-4                                                                              O OCH.sub.3                                                                         -- CH.sub.3                                                                         --  -- -- --  --                                    L-6                                                                               ##STR246##                                                                           A-5                                                                              O --  -- -- OCH.sub.3                                                                         CH.sub.3                                                                         -- --  --                                    L-6                                                                               ##STR247##                                                                           A-6                                                                              O --  -- -- --  -- CH.sub.3                                                                         --  --                                    L-2                                                                              CHCH.sub.2                                                                            A-2                                                                              O CH.sub.3                                                                          O  -- --  -- -- --  --                                    L-2                                                                              CHCH.sub.2                                                                            A-2                                                                              O OCH.sub.3                                                                         O  -- --  -- -- --  --                                    L-2                                                                              CHCH.sub. 2                                                                           A-2                                                                              O CH.sub.3                                                                          CH -- --  -- -- --  --                                    L-2                                                                              CHCH.sub.2                                                                            A-3                                                                              O OCH.sub.3                                                                         -- -- --  -- -- --  --                                    L-2                                                                              CHCH.sub.2                                                                            A-4                                                                              O OCH.sub.3                                                                         -- CH.sub.3                                                                         --  -- -- --  --                                    L-2                                                                              CHCH.sub.2                                                                            A-5                                                                              O --  -- -- OCH.sub.3                                                                         CH.sub.3                                                                         -- --  --                                    L-2                                                                              CHCH.sub.2                                                                            A-6                                                                              O --  -- -- --  -- CH.sub.3                                                                         --  --                                    L-3                                                                              CHCH.sub.2                                                                            A-2                                                                              O CH.sub.3                                                                          O  -- --  -- -- --  --                                    L-3                                                                              CHCH.sub.2                                                                            A-3                                                                              O OCH.sub.3                                                                         -- -- --  -- -- --  --                                    L-3                                                                              CHCH.sub.2                                                                            A-4                                                                              O OCH.sub.3                                                                         -- CH.sub.3                                                                         --  -- -- --  --                                    L-3                                                                              CHCH.sub.2                                                                            A-5                                                                              O --  -- -- OCH.sub.3                                                                         CH.sub.3                                                                         -- --  --                                    L-3                                                                              CHCH.sub.2                                                                            A-6                                                                              O --  -- -- --  -- CH.sub.3                                                                         --  --                                    L-4                                                                              CHCH.sub.2                                                                            A-2                                                                              O CH.sub.3                                                                          O  -- --  -- -- --  --                                    L-4                                                                              CHCH.sub.2                                                                            A-3                                                                              O OCH.sub.3                                                                         -- -- --  -- -- --  --                                    L-4                                                                              CHCH.sub.2                                                                            A-4                                                                              O OCH.sub.3                                                                         -- CH.sub.3                                                                         --  -- -- --  --                                    L-4                                                                              CHCH.sub.2                                                                            A-5                                                                              O --  -- -- OCH.sub.3                                                                         CH.sub.3                                                                         -- --  --                                    L-4                                                                              CHCH.sub.2                                                                            A-6                                                                              O --  -- -- --  -- CH.sub.3                                                                         --  --                                    L-5                                                                              CHCH.sub.2                                                                            A-2                                                                              O CH.sub.3                                                                          O  -- --  -- -- --  --                                    L-5                                                                              CHCH.sub.2                                                                            A-3                                                                              O OCH.sub.3                                                                         -- -- --  -- -- --  --                                    L-5                                                                              CHCH.sub.2                                                                            A-4                                                                              O OCH.sub.3                                                                         -- CH.sub.3                                                                         --  -- -- --  --                                    L-5                                                                              CHCH.sub.2                                                                            A-5                                                                              O --  -- -- OCH.sub.3                                                                         CH.sub.3                                                                         -- --  --                                    L-5                                                                              CHCH.sub.2                                                                            A-6                                                                              O --  -- -- --  -- CH.sub.3                                                                         --  --                                    L-6                                                                              CHCH.sub.2                                                                            A-2                                                                              O CH.sub.3                                                                          O  -- --  -- -- --  --                                    L-6                                                                              CHCH.sub.2                                                                            A-3                                                                              O OCH.sub.3                                                                         -- -- --  -- -- --  --                                    L-6                                                                              CHCH.sub.2                                                                            A-4                                                                              O OCH.sub.3                                                                         -- CH.sub.3                                                                         --  -- -- --  --                                    L-6                                                                              CHCH.sub.2                                                                            A-5                                                                              O --  -- -- OCH.sub.3                                                                         CH.sub.3                                                                         -- --  --                                    L-6                                                                              CHCH.sub.2                                                                            A-6                                                                              O --  -- -- --  -- CH.sub.3                                                                         --  --                                    L-2                                                                              CHCH.sub.2                                                                            A-7                                                                              O --  -- -- --  -- -- CH.sub.3                                                                          OCH.sub.3                             L-2                                                                              CHCH.sub.2                                                                            A-7                                                                              O --  -- -- --  -- -- OCH.sub.3                                                                         OCH.sub.3                             L-2                                                                              CHCH.sub.2                                                                            A-7                                                                              O --  -- -- --  -- -- Cl  OCH.sub.3                             L-2                                                                              CHCH.sub.2                                                                            A-7                                                                              O --  -- -- --  -- -- OCH.sub.3                                                                         OCH.sub.2 CH.sub.3                    __________________________________________________________________________

                                      TABLE Va                                    __________________________________________________________________________    General Structure Va                                                          L  W       A  n X.sub.1                                                                           Y.sub.1                                                                          Y.sub.2                                                                          X.sub.2                                                                           Y.sub.3                                                                          X.sub.3                                                                          X.sub.4                                                                           Y.sub.4                                                                           m.p. (°C.)                 __________________________________________________________________________    L-2                                                                               ##STR248##                                                                           A-2                                                                              O CH.sub.3                                                                          O  -- --  -- -- -   -                                     L-2                                                                               ##STR249##                                                                           A-2                                                                              O OCH.sub.3                                                                         O  -- --  -- -- --  --                                    L-2                                                                               ##STR250##                                                                           A-2                                                                              O CH.sub.3                                                                          CH -- --  -- -- --  --                                    L-2                                                                               ##STR251##                                                                           A-3                                                                              O OCH.sub.3                                                                         -- -- --  -- -- --  --                                    L-2                                                                               ##STR252##                                                                           A-4                                                                              O OCH.sub.3                                                                         -- CH.sub.3                                                                         --  -- -- --  --                                    L-2                                                                               ##STR253##                                                                           A-5                                                                              O --  -- -- OCH.sub.3                                                                         CH.sub.3                                                                         -- --  --                                    L-2                                                                               ##STR254##                                                                           A-6                                                                              O --  -- -- --  -- CH.sub.3                                                                         --  --                                    L-2                                                                              CHCH.sub.2                                                                            A-2                                                                              O CH.sub.3                                                                          O  -- --  -- -- --  --                                    L-2                                                                              CHCH.sub.2                                                                            A-2                                                                              O OCH.sub.3                                                                         O  -- --  -- -- --  --                                    L-2                                                                              CHCH.sub.2                                                                            A-2                                                                              O CH.sub.3                                                                          CH -- --  -- -- --  --                                    L-2                                                                              CHCH.sub.2                                                                            A-3                                                                              O OCH.sub.3                                                                         -- -- --  -- -- --  --                                    L-2                                                                              CHCH.sub.2                                                                            A-4                                                                              O OCH.sub.3                                                                         -- CH.sub.3                                                                         --  -- -- --  --                                    L-2                                                                              CHCH.sub.2                                                                            A-5                                                                              O --  -- -- OCH.sub.3                                                                         CH.sub.3                                                                         -- --  --                                    L-2                                                                              CHCH.sub.2                                                                            A-6                                                                              O --  -- -- --  -- CH.sub.3                                                                         --  --                                    L-2                                                                              CHCH.sub.2                                                                            A-7                                                                              --                                                                              --  -- -- --  -- -- CH.sub.3                                                                          OCH.sub.3                             L-2                                                                              CHCH.sub.2                                                                            A-7                                                                              --                                                                              --  -- -- --  -- -- OCH.sub.3                                                                         OCH.sub.3                             L-2                                                                              CHCH.sub.2                                                                            A-7                                                                              --                                                                              --  -- -- --  -- -- Cl  OCH.sub.3                             __________________________________________________________________________

Formulations

Useful formulations of the compounds of Formula I can be prepared inconventional ways. They include dusts, granules, pellets, solutions,suspensions, emulsions, wettable powders, emulsifiable concentrates andthe like. Many of these may be applied directly. Sprayable formulationscan be extended in suitable media and used at spray volumes of from afew liters to several hundred liters per hectare. High strengthcompositions are primarily used as intermediates for furtherformulation. The formulations, broadly, contain about 0.1% to 99% byweight of active ingredient(s) and at least one of (a) about 0.1% to 20%surfactant(s) and (b) about 1% to 99.9% solid or liquid inertdiluent(s). More specifically, they will contain these ingredients inthe following approximate proportions:

    ______________________________________                                                    Weight Percent*                                                               Active                                                                        Ingredient                                                                            Diluent(s)                                                                              Surfactant(s)                                   ______________________________________                                        Wettable Powders                                                                            20-90      0-74     1-10                                        Oil Suspensions,                                                                             3-50     40-95     0-15                                        Emulsions, Solutions,                                                         (including Emulsifiable                                                       Concentrates)                                                                 Aqueous Suspension                                                                          10-50     40-84     1-20                                        Dusts          1-25     70-99     0-5                                         Granules and Pellets                                                                        0.1-95      5-99.9  0-15                                        High Strength 90-99      0-10     0-2                                         Compositions                                                                  ______________________________________                                         *Active ingredient plus at least one of a Surfactant or a Diluent equals      100 weight percent.                                                      

Lower or higher levels of active ingredient can, of course, be presentdepending on the intended use and the physical properties of thecompound. Higher ratios of surfactant to active ingredient are sometimesdesirable, and are achieved by incorporation into the formulation or bytank mixing.

Typical solid diluents are described in Watkins, et al., "Handbook ofInsecticide Dust Diluents and Carriers", 2nd Ed., Dorland Books,Caldwell, N.J., but other solids, either mined or manufactured, may beused. The more absorptive diluents are preferred for wettable powdersand the denser ones for dusts. Typical liquid diluents and solvents aredescribed in Marsden, "Solvents Guide," 2nd Ed., Interscience, New York,1950. Solubility under 0.1% is preferred for suspension concentrates;solution concentrates are preferably stable against phase separation at0° C. "McCutcheon's Detergents and Emulsifiers Annual", MC PublishingCorp., Ridgewood, N.J., as well as Sisely and Wood, "Encyclopedia ofSurface Active Agents", Chemical Publishing Co., Inc., New York, 1964,list surfactants and recommended uses. All formulations can containminor amounts of additives to reduce foaming, caking, corrosion,microbiological growth, etc.

The methods of making such compositions are well known. Solutions areprepared by simply mixing the ingredients. Fine solid compositions aremade by blending and, usually, grinding as in a hammer or fluid energymill. Suspensions are prepared by wet milling (see, for example,Littler, U.S. Pat. No. 3,060,084). Granules and pellets may be made byspraying the active material upon preformed granular carriers or byagglomeration techniques. See J. E. Browning, "Agglomeration", ChemicalEngineering, Dec. 4, 1967, pp. 147ff. and "Perry's Chemical Engineer'sHandbook", 5th Ed., McGraw-Hill, New York, 1973, pp. 8-57ff.

For further information regarding the art of formulation, see forexample:

H. M. Loux, U.S. Pat. No. 3,235,361, Feb. 15, 1966, Col. 6, line 16through Col. 7, line 19 and Examples 10 through 41;

R. W. Luckenbaugh, U.S. Pat. No. 3,309,192, Mar. 14, 1967, Col. 5, line43 through Col. 7, line 62 and Examples 8, 12, 15, 39, 41, 52, 53, 58,132, 138-140, 162-164, 166, 167 and 169-182;

H. Gysin and E. Knusli, U.S. Pat. No. 2,891,855, June 23, 1959, Col. 3,line 66 through Col. 5, line 17 and Examples 1-4;

G. C. Klingman, "Weed Control as a Science", John Wiley and Sons, Inc.,New York, 1961, pp. 81-96; and

J. D. Fryer and S. A. Evans, "Weed Control Handbook", 5th Ed., BlackwellScientific Publications, Oxford, 1968, pp. 101-103.

In the following examples, all parts are by weight unless otherwiseindicated.

EXAMPLE 6

    ______________________________________                                        Wettable Powder                                                               ______________________________________                                        2-(1-cyclohexen-2-yl)-N--[4-methoxy-6-methylpyrimidin-                                                    80%                                               2-yl)aminocarbonyl]-3-thiophenesulfonamide                                    sodium alkylnaphthalenesulfonate                                                                          2%                                                sodium ligninsulfonate      2%                                                synthetic amorphous silica  3%                                                kaolinite                   13%                                               ______________________________________                                    

The ingredients are blended, hammer-milled until all the solids areessentially under 50 microns, reblended, and packaged.

EXAMPLE 7

    ______________________________________                                        Wettable Powder                                                               ______________________________________                                        2-(1-cyclohexen-2-yl)-N--[4-methoxy-6-methyl-                                                           50%                                                 1,3,5-triazin-2-yl)aminocarbonyl]-3-thiophene-                                sulfonamide                                                                   sodium alkylnaphthalenesulfonate                                                                         2%                                                 low viscosity methyl cellulose                                                                           2%                                                 diatomaceous earth        46%                                                 ______________________________________                                    

The ingredients are blended, coarsely hammer-milled and then air-milledto produce particles essentially all below 10 microns in diameter. Theproduct is reblended before packaging.

EXAMPLE 8

    ______________________________________                                        Granule                                                                       ______________________________________                                        Wettable Powder of Example 7                                                                          5%                                                    attapulgite granules   95%                                                    (U.S.S. 20-40 mesh; 0.84-0.42 mm)                                             ______________________________________                                    

A slurry of wettable powder containing 25% solids is sprayed on thesurface of attapulgite granules in a double-cone blender. The granulesare dried and packaged.

EXAMPLE 9

    ______________________________________                                        Extruded Pellet                                                               ______________________________________                                        2-(1-cyclohexen-2-yl)-N--[4-methoxy-6-methylpyrimidin-                                                     25%                                              2-yl)aminocarbonyl]-3-thiophenesulfonamide                                    anhydrous sodium sulfate     10%                                              crude calcium ligninsulfonate                                                                               5%                                              sodium alkylnaphthalenesulfonate                                                                            1%                                              calcium/magnesium bentonite  59%                                              ______________________________________                                    

The ingredients are blended, hammer-milled and then moistened with about12% water. The mixture is extruded as cylinders about 3 mm diameterwhich are cut to produce pellets about 3 mm long. These may be useddirectly after drying, or the dried pellets may be crushed to pass aU.S.S. No. 20 sieve (0.84 mm openings). The granules held on a U.S.S.No. 40 sieve (0.42 mm openings) may be packaged for use and the finesrecycled.

EXAMPLE 10

    ______________________________________                                        Oil Suspension                                                                ______________________________________                                        2-(1-cyclohexen-2-yl)-N--[(4-methoxy-6-methyl-                                                          25%                                                 1,3,5-triazin-2-yl)aminocarbonyl]-3-thiophene-                                sulfonamide                                                                   polyoxyethylene sorbitol hexaoleate                                                                      5%                                                 highly aliphatic hydrocarbon oil                                                                        70%                                                 ______________________________________                                    

The ingredients are ground together in a sand mill until the solidparticles have been reduced to under about 5 microns. The resultingthick suspension may be applied directly, but preferably after beingextended with oils or emulsified in water.

EXAMPLE 11

    ______________________________________                                        Wettable Powder                                                               ______________________________________                                        2-(1-cyclohexen-2-yl)-N--[4-methoxy-6-methylpyrimidin-                                                     20%                                              2-yl)aminocarbonyl]-3-thiophenesulfonamide                                    sodium alkylnaphthalenesulfonate                                                                           4%                                               sodium ligninsulfonate       4%                                               low viscosity methyl cellulose                                                                             3%                                               attapulgite                  69%                                              ______________________________________                                    

The ingredients are thoroughly blended. After grinding in a hammer-millto produce particles essentially all below 100 microns, the material isreblended and sifted through a U.S.S. No. 50 sieve (0.3 mm opening) andpackaged.

EXAMPLE 12

    ______________________________________                                        Low Strength Granule                                                          ______________________________________                                        2-(1-cyclohexen-2-yl)-N--[4-methoxy-6-methyl-                                                           1%                                                  1,3,5-triazin-2-yl)aminocarbonyl]-3-thiophene-                                sulfonamide                                                                   N,N--dimethylformamide    9%                                                  attapulgite granules      90%                                                 (U.S.S. 20-40 sieve)                                                          ______________________________________                                    

The active ingredient is dissolved in the solvent and the solution issprayed upon dedusted granules in a double cone blender. After sprayingof the solution has been completed, the blender is allowed to run for ashort period and then the granules are packaged.

EXAMPLE 13

    ______________________________________                                        Aqueous Suspension                                                            ______________________________________                                        2-(1-cyclohexen-2-yl)-N--[4-methoxy-6-methyl-                                                            40%                                                1,3,5-triazin-2-yl)aminocarbonyl]-3-thiophene-                                sulfonamide                                                                   polyacrylic acid thickener                                                                              0.3%                                                dodecylphenol polyethylene glycol ether                                                                 0.5%                                                disodium phosphate          1%                                                monosodium phosphate      0.5%                                                polyvinyl alcohol         1.0%                                                water                     56.7%                                               ______________________________________                                    

The ingredients are blended and ground together in a sand mill toproduce particles essentially all under 5 microns in size.

EXAMPLE 14

    ______________________________________                                        Solution                                                                      ______________________________________                                        2-(1-cyclohexen-2-yl)-N--[4-methoxy-6-methylpyrimidin-2-                                                     5%                                             yl)aminocarbonyl]-3-thiophenesulfonamide, ammonium salt                       water                         95%                                             ______________________________________                                    

The salt is added directly to the water with stirring to produce thesolution, which may then be packaged for use.

EXAMPLE 15

    ______________________________________                                        Low Strength Granule                                                          ______________________________________                                        2-(1-cyclohexen-2-yl)-N--[4-methoxy-6-methylpyrimidin-                                                      0.1%                                            2-yl)aminocarbonyl]-3-thiophenesulfonamide                                    attapulgite granules         99.9%                                            (U.S.S. 20-40 mesh)                                                           ______________________________________                                    

The active ingredient is dissolved in a solvent and the solution issprayed upon dedusted granules in a double-cone blender. After sprayingof the solution has been completed, the material is warmed to evaporatethe solvent. The material is allowed to cool and then packaged.

EXAMPLE 16

    ______________________________________                                        Granule                                                                       ______________________________________                                        2-(1-cyclohexen-2-yl)-N--[4-methoxy-6-methyl-                                                           80%                                                 1,3,5-triazin-2-yl)aminocarbonyl]-3-thiophene-                                sulfonamide                                                                   wetting agent              1%                                                 crude ligninsulfonate salt (containing                                                                  10%                                                 5-20% of the natural sugars)                                                  attapulgite clay           9%                                                 ______________________________________                                    

The ingredients are blended and milled to pass through a 100 meshscreen. This material is then added to a fluid bed granulator, the airflow is adjusted to gently fluidize the material, and a fine spray ofwater is sprayed onto the fluidized material. The fluidization andspraying are continued until granules of the desired size range aremade. The spraying is stopped, but fluidization is continued, optionallywith heat, until the water content is reduced to the desired level,generally less than 1%. The material is then discharged, screened to thedesired size range, generally 14-100 mesh (1410-149 microns), andpackaged for use.

EXAMPLE 17

    ______________________________________                                        High Strength Concentrate                                                     ______________________________________                                        2-(1-cyclohexen-2-yl)-N--[4-methoxy-6-methylpyrimidin-                                                    99%                                               2-yl)aminocarbonyl]-3-thiophenesulfonamide                                    silica aerogel              0.5%                                              synthetic amorphous silica  0.5%                                              ______________________________________                                    

The ingredients are blended and ground in a hammer-mill to produce amaterial essentially all passing a U.S.S. No. 50 screen (0.3 mmopening). The concentrate may be formulated further if necessary.

EXAMPLE 18

    ______________________________________                                        Wettable Powder                                                               ______________________________________                                        N--[(4-methoxy-6-methylpyrimidin-2-yl)aminocar-                                                           90%                                               bonyl]-1-methyl-4-(1-propenyl)-1H--pyrazole-                                  5-sulfonamide                                                                 dioctyl sodium sulfosuccinate                                                                             0.1%                                              synthetic fine silica       9.9%                                              ______________________________________                                    

The ingredients are blended and ground in a hammer-mill to produceparticles essentially all below 100 microns. The material is siftedthrough a U.S.S. No. 50 screen and then packaged.

EXAMPLE 19

    ______________________________________                                        Wettable Powder                                                               ______________________________________                                        N--[(4-methoxy-6-methylpyrimidin-2-yl)aminocar-                                                           40%                                               bonyl]-1-methyl-4-(1-propenyl)-1H--pyrazole-                                  5-sulfonamide                                                                 sodium ligninsulfonate      20%                                               montmorillonite clay        40%                                               ______________________________________                                    

The ingredient are thoroughly blended, coarsely hammer-milled and thenair-milled to produce particles essentially all below 10 microns insize. The material is reblended and then packaged.

EXAMPLE 20

    ______________________________________                                        Oil Suspension                                                                ______________________________________                                        N--[(4-methoxy-6-methylpyrimidin-2-yl)aminocar-                                                           35%                                               bonyl]-1-methyl-4-(1-propenyl)-1H--pyrazole-                                  5-sulfonamide                                                                 blend of poly alcohol carboxylic                                                                           6%                                               esters and oil soluble petroleum                                              sulfonates                                                                    xylene                      59%                                               ______________________________________                                    

The ingredients are combined and ground together in a sand mill toproduce particles essentially all below 5 microns. The product can beused directly, extended with oils, or emulsified in water.

EXAMPLE 21

    ______________________________________                                        Dust                                                                          ______________________________________                                        N--[(4-methoxy-6-methylpyrimidin-2-yl)aminocar-                                                           10%                                               bonyl]-1-methyl-4-(1-propenyl)-1H--pyrazole-                                  5-sulfonamide                                                                 attapulgite                 10%                                               Pyrophyllite                80%                                               ______________________________________                                    

The active ingredient is blended with attapulgite and then passedthrough a hammer-mill to produce particles substantially all below 200microns. The ground concentrate is then blended with powderedpyrophyllite until homogeneous.

EXAMPLE 22

    ______________________________________                                        Emulsifiable Concentrate                                                      ______________________________________                                        N--[(4-methoxy-6-methylpyrimidin-2-yl)aminocar-                                                           10%                                               bonyl]-1-methyl-4-(1-propenyl)-1H--pyrazole-                                  5-sulfonamide                                                                 chlorobenzene               84%                                               sorbitan monostearate and polyoxyethylene                                                                  6%                                               condensates thereof                                                           ______________________________________                                    

The ingredients are combined and stirred to produce a solution which canbe emulsified in water for application.

Utility

Test results indicate that the compounds of the present invention arehighly active preemergent or postemergent herbicides or plant growthregulants. Many of them have utility for broad-spectrum pre- and orpost-emergence weed control in areas where complete control of allvegetation is desired, such as around fuel storage tanks, ammunitiondepots, industrial storage areas, parking lots, drive-in theaters,around billboards, highway and railroad structures. Some of thecompounds have utility for selective weed control in crops such as riceand wheat. Alternatively, the subject compounds are useful to modifyplant growth.

The rates of application for the compounds of the invention aredetermined by a number of factors, including their use as plant growthmodifiers or as herbicides, the crop species involved, the types ofweeds to be controlled, weather and climate, formulations selected, modeof application, amount of foliage present, etc. In general terms, thesubject compounds should be applied at levels of arount 0.05 to 10kg/ha, the lower rates being suggested for use on lighter soils and/orthose having a low organic matter content, for plant growth modificationor for situations where only short-term persistence is required.

The compounds of the invention may be used in combination with any othercommercial herbicide, examples of which are those of the triazine,triazole, uracil, urea, amide, diphenylether, carbamate and bipyridyliumtypes.

The herbicidal properties of the subject compounds were discovered in anumber of greenhouse tests. The test procedures and results follow.

Test A

Seeds of crabgrass (Digitaria sp.), barnyardgrass (Echinochloacrusgalli), wild oats (Avena fatua), velvetleaf (Abutilon theophrasti),cheatgrass (Bromus secalinus), morningglory (Ipomoea sp.), cocklebur(Xanthium sp.), sorghum, corn, soybean, rice, wheat and nutsedge tubers(Cyperus rotundus) were planted in a growth medium and treatedpre-emergence with the chemicals dissolved in a non-phytotoxic solvent.At the same time, cotton having five leaves (including cotyledonaryones), bush beans with the third trifoliate leaf expanding, crabgrass,barnyardgrass and wild oats with two leaves, sicklepod with three leaves(including cotyledonary ones), morningglory and cocklebur with fourleaves (including the cotyledonary ones), sorghum and corn with fourleaves, soybean with two cotyledonary leaves, rice with three leaves,wheat with one leaf, and nutsedge with three to five leaves weresprayed. Treated plants and controls were maintained in a greenhouse forsixteen days, whereupon all species were compared to controls andvisually rated for response to treatment. The ratings are based on anumerical scale extending from 0=no injury, to 10=complete kill. Theaccompanying descriptive symbols have the following meanings:

    ______________________________________                                               C =   chlorosis or necrosis;                                                  B =   burn;                                                                   D =   defoliation;                                                            E =   emergence inhibition;                                                   G =   growth retardation;                                                     H =   formative effects;                                                      U =   unusual pigmentation                                                    X =   axillary stimulation;                                                   S =   albinism; and                                                           6Y =  abscised buds or flowers.                                        ______________________________________                                    

    ______________________________________                                        Compounds                                                                     Compound  R.sub.3  E     X       Y     Z                                      ______________________________________                                         ##STR255##                                                                   ______________________________________                                         1        H        Se    CH.sub.3                                                                              CH.sub.3                                                                            CH                                      2        H        Se    CH.sub.3                                                                              OCH.sub.3                                                                           CH                                      3        H        Se    OCH.sub.3                                                                             OCH.sub.3                                                                           CH                                      4        H        Se    CH.sub.3                                                                              CH.sub.3                                                                            N                                       5        H        Se    CH.sub.3                                                                              OCH.sub.3                                                                           N                                       6        H        Se    OCH.sub.3                                                                             OCH.sub.3                                                                           N                                       7        CH.sub.3 Se    CH.sub.3                                                                              CH.sub.3                                                                            CH                                      8        CH.sub.3 Se    CH.sub.3                                                                              OCH.sub.3                                                                           CH                                      9        CH.sub.3 Se    OCH.sub.3                                                                             OCH.sub.3                                                                           CH                                     10        CH.sub.3 Se    CH.sub.3                                                                              CH.sub.3                                                                            N                                      11        CH.sub.3 Se    CH.sub.3                                                                              OCH.sub.3                                                                           N                                      12        CH.sub.3 Se    OCH.sub.3                                                                             OCH.sub.3                                                                           N                                      13        H        S     CH.sub.3                                                                              CH.sub.3                                                                            CH                                     14        H        S     OCH.sub.3                                                                             CH.sub.3                                                                            CH                                     15        H        S     OCH.sub.3                                                                             OCH.sub.3                                                                           CH                                     16        H        S     CH.sub.3                                                                              CH.sub.3                                                                            N                                      17        H        S     OCH.sub.3                                                                             OCH.sub.3                                                                           N                                      ______________________________________                                         ##STR256##                                                                   ______________________________________                                        18                    OCH.sub.3                                                                              CH.sub.3                                                                            CH                                       19                   OCH.sub.3 OCH.sub.3                                                                           CH                                       20                   OCH.sub.3 OCH.sub.3                                                                           N                                        ______________________________________                                         ##STR257##                                                                   ______________________________________                                        21                   CH.sub.3  CH.sub.3                                                                            CH                                       22                   OCH.sub.3 CH.sub.3                                                                            CH                                       23                   OCH.sub.3 OCH.sub. 3                                                                          CH                                       24                   OCH.sub.3 CH.sub.3                                                                            N                                        25                   OCH.sub.3 OCH.sub.3                                                                           N                                        26                   Cl        OCH.sub.3                                                                           CH                                       ______________________________________                                    

    TABLE A      Compound 1 Compound 2 Compound 3 Compound 4 Compound 5 Compound 6     Compound 7 Compound 8 Compound 9 Compound 10 Compound 11 Compound 12     Rate (kg/ha) 0.40 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0     .05       POSTEMERGENCE Morningglory 0 0 2C,6H 1C 0 2C 1C 6G 5C,8G 4C,9G 2C,7G     10C 9C Cocklebur 0 0 2G 1C,3G 3G 2C,8H 2C,4H 2C,8G 8G,9G 3C,8G 6G 4C,8G     7G Velvetleaf 2G 0 3C,8G 5C,9G 0 4C,9G 4C,8G 5C,9G 9C 10C 9C 9C 9C     Nutsedge 0 0 2C,5G 5G 0 0 0 3C,7G 3C,8G 9C 0 0 0 Crabgrass 0 0 2G 0 0 0     0 2G 3G 0 0 3G 0 Barnyardgrass 4H 0 2C,7H 3C,8H 0 0 0 3C,9H 2C,9H 5C,9H     3C,5H 3C,8H 2C,5H Cheatgrass 0 0 5G 0 0 0 0 0 4G 4G 0 0 0 Wild Oats 0 0     2C,4G 0 0 0 0 3C,9G 2C,7G 0 0 0 0 Wheat 0 0 3G 0 0 0 0 6G 5G 0 0 0 0     Corn 2C,7H 0 3C,8G 0 0 2H 1H 2C,8G 3C,9G 3C,9H 9G 3C,8H 2C,8H Soybean 2H     0 3H,9G 4C,9G 0 2C,9G 7H 3C,9G 5C,9G 5C,9G 4C,9G 5C,9G 4C,9G Rice 6G 0     7G 8G 0 0 0 3C,9G 2C,8G 2C,8G 3C,9G 5G 0 Sorghum 2C,5H 0 3C,8G 7H 0 2G 0     2C,9G 3C,9H 3C,8H 2C,8H 4C,9H 2C,5H Sugar Beets 3C,6G 2H 2C,8G 9C 0     2C,5H 3C,5G 4C,9G 7G 9C 9C 9C 9C Cotton 3C,7H 0 3C,7H 2C,8G 0 3C,8H     3C,6H 4C,9G 4C,9G 5C,9G 9H 9C 9C PREEMERGENCE Morningglory 3G 0 8G 4G 0     2C 0 7G 9G 8G 2C 9G 9G Cocklebur 1H 0 7H 7G 0 2C 0 7G 9G 8H 5G -- 7H     Velvetleaf 2G 0 8G 7G 0 2G 0 8G 10C 9C 8G 5C,9G 5C,9G Nutsedge 5G 0 0 7G     0 0 0 8G 9G 8G 0 0 0 Crabgrass 0 0 2G 0 0 0 0 2G 5G 3G 0 0 0 Barnyardgras     s 0 0 2C,7G 4G 0 0 0 7H 9H 3C,9H 0 2C 1C Cheatgrass 5G 0 0 2G 0 0 0 9G     3C,9G 5C,9G 6G 0 0 Wild Oats 5G 0 2C,7G 0 0 0 0 8G 4C,9H 8G 2C,5G 2G 0     Wheat 4G 0 4G 0 0 0 0 8G 5C,9H 4G 0 0 0 Corn 2C,6H 2G 2C,8H 2C,8G 0 2G 0     2C,9G 5C,9H 8H 2C,7G 8G 5G Soybean 2C,2H 0 3C,7G 3C,6G 0 1C 0 3C,5H     2C,8G 7H 6G 8H 8H Rice 7H 0 7G 2C,7G 0 0 0 10E 10H 10E 8H 8G 5G Sorghum     7H 0 3C,9H 2C,7H 0 2G 0 5C,9H 10H 3C,8H 6G 3C,8H 3G Sugar Beets 3C,8G 0     2C,8G 8G 0 2C,6G 0 9C 10C 9C 9C 10C 10C Cotton 5G 0 7G 5G 0 6G 0 9G 9G     9G 6H 9G 9G       Compound 13 Compound 14 Compound 16 Compound 17 Compound 18 Compound     19 Compound 20 Cmpd. 21 Cmpd. 22 Cmpd. 23 Cmpd.24 Cmpd. 25 Cmpd. 26 Rate     (kg/ha) 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0.05 0     .05        POSTEMERGENCE Morningglory 1H 4C,9G 3C,8H 1H 2C,7G 3C,8G 2C,7G 2H,5G     10C 9C 4C,8G 10C 10C 4C,9G Cocklebur 7H 4C,9G 3C,8H 0 2C 9C 9C 9H 2C,9H     9C 10C 9C 10C 10C Velvetleaf 8H 9C 10C 2C,7G 5C,9G 9C 4C,9G 8G 10C 9C 9G     10C 3C,8G 3C,8G Nutsedge 7G 3C,6G 5C,9G 0 0 3C,8G 2C,9G 0 0 5G 7G 0 3G 0     Crabgrass 2G 2C,5G 1C 0 0 3G 0 0 0 2G 0 0 0 0 Barnyardgrass 3H 4C,9H     3C,8H 0 0 3C,9H 4C,8H 0 6H 2C,6H 2H 1H 0 0 Cheatgrass 5G 2C,5G 0 0 0 6G     2G 0 5G 3G 5G 0 0 0 Wild Oats 0 3C,3H 0 0 0 0 2C 0 2C 0 0 0 0 0 Wheat 0     2G 0 0 0 2G 0 0 0 0 0 0 0 0 Corn 3H 3C,9H 2G 0 0 3C,9H 2C,9H 0 3C,8H 0 0     0 0 0 Soybean 0 3C,7H 3H,9G 1C,1H 2C,9G 4C,9H 3C,8H 2C,3H 3C,9G 4C,9G     5C,9G 9C 9C 2C,5G Rice 7G 8G 8G 5G 0 2C,6G 5G 0 3G 2G 2G 1G 0 0 Sorghum     2C,7G 3C,9G 2C,6G 2G 2C 4C,9H 3C,5G 3H 3C,8H 2C,8G 2C,6G 2C,6G 2G 2C,5G     Sugar Beets 4C,9G 9C 9C 4C,8H 9C 4C,9H 2C,8G 3C,7G 2C,7G 4C,9G 9C 9C 9C     3H Cotton 4C,8H 9C 5C,9G 3C,4G 9H 9C 9C 2C,8G 9C 9C 9C 10C 10C 10C     PREEMERGENCE Morningglory 5G 7G 6G 1H 5G 7H 9G 3C,7H 9G 9G 7G 9G 9G 6G     Cocklebur 0 6G 2C,5G 0 3G 7H 7H 1C 8G 8H 8H 8G 8H 3H Velvetleaf 5G 8G 9G     0 5G 8G 8G 0 8G 8G 7G 8G 6G 3G Nutsedge 0 5G 5G 0 0 9G 10E 0 4G 8G 7G 0     0 0 Crabgrass 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Barnyardgrass 1C 3C,7H 2C,2H 0     2C 6H 4G 0 3G 2C,7G 4G 0 0 0 Cheatgrass 0 5G 5G 0 0 6G 0 0 4G 8G 5G 0 0     0 Wild Oats 3G 2C,8G 0 0 0 1C 0 0 0 2C 0 0 0 0 Wheat 2G 5G 0 0 0 2G 5G 0     2G 0 0 0 0 0 Corn 2C,4G 2C,8G 3C,8H 0 0 9G 8G 2C,6G 5G 2C,5G 2C,2G 3G 2G     0 Soybean 2C,2H 3C,8H 6H 0 5H 8H 2C,3G 3C,3H 0 5G 2G 3G 0 0 Rice 2G 7H     3C,8H 0 3G 5G 5G 5G 7G 6G 2G 0 0 0 Sorghum 2C 3C,8H 3C,5G 0 0 2C,8G     2C,6H 2C,4G 4C,9G 2C,8H 3C,7H 3C,8G 3C,5G 2C,5G Sugar Beets 6G 9G 9G 0     4C,9G 9G 10C 4G 8G 4C,9G 2C,8G 4C,9G 9G 6G Cotton 4G 8G 8G 0 7G 9G 9G 7G     5G 8G 5G 9G 8G 5G

What is claimed is:
 1. A compound of the formula ##STR258## R is H orCH₃ ; W₃ is O or S;n is 0 or 1; E is S(O)_(p) or Se; p is 0, 1 or 2; R₁is H, C₁ -C₃ alkyl, C₁ -C₃ haloalkyl, halogen, nitro, CH₂ CN, CH₂ OCH₃,CH₂ SCH₃, CN, C₁ -C₃ alkoxy, SO₂ NR^(I) R^(II), C₁ -C₃ alkylthio, C₁ -C₃alkylsulfinyl, C₁ -C₃ alkylsulfonyl or CO₂ R^(III) ; R^(I) is H, C₁ -C₄alkyl, C₂ -C₃ cyanoalkyl, methoxy or ethoxy; R^(II) is H, C₁ -C₄ alkylor C₃ -C₄ alkenyl; or R^(I) and R^(II) may be taken together as --(CH₂)₃--, --(CH₂)₄ --, --(CH₂)₅ -- or --CH₂ CH₂ OCH₂ CH₂ --; R^(III) is C₁ -C₄alkyl, C₃ -C₄ alkenyl, C₃ -C₄ alkynyl, C₂ -C₄ haloalkyl, C₂ -C₄cyanoalkyl, C₅ -C₆ cycloalkyl, C₄ -C₇ cycloalkylalkyl or C₂ -C₄alkoxyalkyl; R₂ is C₁ -C₃ alkyl; W is W₁ or W₂ ; W₁ is C₂ -C₈ alkenyl orC₄ -C₇ cycloalkenyl either of which may be optionally substituted with1-3 atoms of F, Cl or Br, OH, CN, NO₂, C₁ -C₃ alkoxy, C₁ -C₃ alkylthio,C₁ -C₃ alkylsulfinyl, C₁ -C₃ alkylsulfonyl, amino, C₂ -C₄ alkenyl, C₁-C₃ alkylamino, di(C₁ -C₃ alkyl)amino, (C₁ -C₃ alkylamino)sulfamoyl,di(C₁ -C₃ alkylamino)sulfamoyl, OC(O)C₁ -C₃ alkyl, C(O)C₁ -C₃ alkoxy,OC(O)C₁ -₃ alkoxy, OSO₂ C₁ -C₃ alkyl, OSO₂ C₆ H₅, OSO₂ --4--CH₃ -- C₆H₄, phenyl or phenyl substituted with halogen, CH₃, OCH₃, SCH₃ or NO₂ ;W₂ is C₂ alkynyl which may be substituted with phenyl or phenylsubstituted with halogen, CH₃, OCH₃, SCH₃ or NO₂ or W₂ is C₃ -C₈ alkynylwhich may be optionally substituted with 1-3 atoms of F, Cl or Br, OH,CN, NO₂, C₁ -C₃ alkoxy, C₁ -C₃ alkylthio, C₁ -C₃ alkylsulfinyl, C₁ -C₃alkylsulfonyl, amino, C₁ -C₃ alkylamino, di(C₁ -C₃ alkyl)amino, (C₁ -C₃alkylamino)sulfamoyl, di(C₁ -C₃ alkylamino)sulfamoyl, OC(O)C₁ -C₃ alkyl,OC(O)C₁ -C₃ alkoxy, OSO₂ C₁ -C₃ alkyl, OSO₂ C₆ H₅, OSO₂ --4--CH₃ --C₆H₄, phenyl or phenyl substituted with halogen, CH₃, OCH₃, SCH₃ or NO₂ ;R₃ is H or C₁ -C₄ alkyl; ##STR259## X is H, C₁ -C₄ alkyl, C₁ -C₄ alkoxy,C₁ -C₄ haloalkoxy, C₁ -C₄ haloalkyl, C₁ -C₄ haloalkylthio, C₁ -C₄alkylthio, halogen, C₂ -C₅ alkoxyalkyl, C₂ -C₅ alkoxyalkoxy, amino, C₁-C₃ alkylamino or di(C₁ -C₃ alkyl)amino; Y is H, C₁ -C₄ alkyl, C₁ -C₆alkoxy, C₁ -C₆ haloalkoxy, C₁ -C₄ haloalkylthio, C₁ -C₄ alkylthio, C₂-C₅ alkoxyalkyl, C₂ -C₅ alkoxyalkoxy, amino, C₁ -C₃ alkylamino, di(C₁-C₃ alkyl)amino, C₃ -C₄ alkenyloxy, C₃ -C₄ alkynyloxy, C₂ -C₅alkylthioalkyl, C₁ -C₄ haloalkyl, C₃ -C₅ cycloalkyl, C₂ -C₄ alkynyl,##STR260## m is 2 or 3; L₁ and L₂ are independently O or S; R₄ and R₅are independently C₁ -C₂ alkyl; R₆ is H or CH₃ ; Z is CH; and theiragriculturally suitable salts; provided that (a) when X is Cl, F, Br orI, then Y is OCH₃, OC₂ H₅, N(OCH₃)CH₃, NHCH₃, N(CH₃)₂ or OCF₂ H; (b)when L is L-2 or L-3, then the W substituent and the sulfonylurea bridgeare on adjacent carbon atoms; (c) when W₁ is C₃ alkenyl, then L is L-3,L-4, L-5 or L-6; (d) when L is L-1, then n is 1 and W is W₂ ; (e) when Lis L-1 and W₂ is C₂ or C₃ alkynyl, said group must be substituted; (f)when W₁ is C₃ -C₈ alkenyl or C₄ -C₇ cycloalkenyl substituted with OH,then the OH substituent is not bonded directly to the oelfinic group;(g) when L is L-3, then the sulfonylurea bridge is bonded at the 3- or5-position; (h) when W₃ is S, then R is H and Y is CH₃, OCH₃, OC₂ H₅,CH₂ OCH₃, C₂ H₅, CF₃, SCH₃, OCH₂ CH═CH₂, OCH₂ C.tbd.CH, OCH₂ CH₂ OCH₃ orCH(OCH₃)₂ ; (i) when the total number of carbon atoms of X and Y isgreater than four, then the number of carbons of R₁ must be less than orequal to two and the number of carbons of W must be less than or equalto four; and (j) when L is L-2, L-3, L-4 or L-5, then W₁ is other thanC₂ -C₈ alkenyl substituted with 1-3 atoms of F, Cl or Br.
 2. Thecompounds of claim 1 wherein R is H; and W₃ is O.
 3. The compounds ofclaim 2 where R₁ is H, F, Cl, NO₂, C₁ -C₂ alkyl, C₁ -C₂ haloalkyl, C₁-C₂ alkoxy, C₁ -C₂ alkylthio, CH₂ OCH₃ or CH₂ SCH₃, and is not para tothe sulfonylurea bridge.
 4. The compounds of claim 3 where X is CH₃,OCH₃, OC₂ H₅, Cl, F, Br, OCF₂ H, CH₂ F, OCH₂ CH₂ F, OCH₂ CHF₂, OCH₂ CF₃,CF₃, CH₂ Cl or CH₂ Br; and Y is H, C₁ -C₃ alkyl, OCH₃, OC₂ H₅, CH₂ OCH₃,NHCH₃, N(OCH₃)CH₃, N(CH₃)₂, CF₃, SCH₃, OCH₂ CH═CH₂, OCH₂ C.tbd.CH, CH₂OC₂ H₅, OCH₂ CH₂ OCH₃, CH₂ SCH₃, OCF₂ H, SCF₂ H, cyclopropyl, C.tbd.CHor C.tbd.CCH₃.
 5. The compounds of claim 4 where W₁ is C₂ -C₅ alkenylwhich may be optionally substituted by 1-3 atoms of F, Cl or Br, OH,OCH₃, OC(O)CH₃, OSO₂ CH₃, CN or SCH₃, or W₁ is C₅ -C₆ cycloalkenyl; andW₂ is C.tbd.CC₆ H₅ or C₃ -C₅ alkynyl which may be optionally substitutedby 1-3 atoms of F, Cl or Br, OH, OCH₃, OC(O)CH₃, CN or SCH₃.
 6. Thecompounds of claim 5 where X is CH₃, OCH₃, OC₂ H₅, Cl or OCF₂ H; Y isCH₃, C₂ H₅, OCH₃, CH₂ OCH₃, CH(OCH₃)₂, OCF₂ H, NHCH₃, N(CH₃)₂ orcyclopropyl; and R₁ is H, CH₃ OCH₃ or Cl.
 7. The compounds of claim 6where L is L-1.
 8. The compounds of claim 6 where L is L-2; and W is W₁.9. The compounds of claim 6 where L is L-2; and W is W₂.
 10. Thecompounds of claim 6 where L is L-3; and W is W₁.
 11. The compounds ofclaim 6 where L is L-3; and W is W₂.
 12. The compounds of claim 6 whereL is L-4; and W is W₁.
 13. The compounds of claim 6 where L is L-4; andW is W₂.
 14. The compounds of claim 6 where L is L-5; and W is W₁. 15.The compounds of claim 6 where L is L-5; and W is W₂.
 16. The compoundsof claim 6 where L is L-6; and W is W₁.
 17. The compounds of claim 6where L is L-6; and W is W₂.
 18. The compounds of claim 6 where L isL-7.
 19. The compound of claim 1 that is2-(1-cyclohexen-2-yl)-N-[4-methoxy-6-methylpyrimidin-2-yl)aminocarbonyl]-3-thiophenesulfonamide.20. The compound of claim 1 that isN-[(4-methoxy-6-methylpyrimidin-2-yl)aminocarbonyl]-1-methyl-4-(1-propenyl)-1H-pyrazole-5-sulfonamide.21. An agriculturally suitable composition for controlling the growth ofundesired vegetation comprising an effective amount of a compound ofclaim 1 and at least one of the following: surfactant, solid or liquiddiluent.
 22. An agriculturally suitable composition for controlling thegrowth of undesired vegetation comprising an effective amount of acompound of claim 2 and at least one of the following: surfactant, solidor liquid diluent.
 23. An agriculturally suitable composition forcontrolling the growth of undesired vegetation comprising an effectiveamount of a compound of claim 3 and at least one of the following:surfactant, solid or liquid diluent.
 24. An agriculturally suitablecomposition for controlling the growth of undesired vegetationcomprising an effective amount of a compound of claim 4 and at least oneof the following: surfactant, solid or liquid diluent.
 25. Anagriculturally suitable composition for controlling the growth ofundesired vegetation comprising an effective amount of a compound ofclaim 5 and at least one of the following: surfactant, solid or liquiddiluent.
 26. An agriculturally suitable composition for controlling thegrowth of undesired vegetation comprising an effective amount of acompound of claim 6 and at least one of the following: surfactant, solidor liquid diluent.
 27. A method for controlling the growth of undesiredvegetation which comprises applying to the locus to be protected aneffective amount of a compound of claim
 1. 28. A method for controllingthe growth of undesired vegetation which comprises applying to the locusto be protected an effective amount of a compound of claim
 2. 29. Amethod for controlling the growth of undesired vegetation whichcomprises applying to the locus to be protected an effective amount of acompound of claim
 3. 30. A method for controlling the growth ofundesired vegetation which comprises applying to the locus to beprotected an effective amount of a compound of claim
 4. 31. A method forcontrolling the growth of undesired vegetation which comprises applyingto the locus to be protected an effective amount of a compound of claim5.
 32. A method for controlling the growth of undesired vegetation whichcomprises applying to the locus to be protected an effective amount of acompound of claim 6.